FAQ

threo-3-hydroxyaspartate ammonia-lyase activity

Known as: L-threo-3-hydroxyaspartate dehydratase activity, threo-3-hydroxy-L-aspartate ammonia-lyase (oxaloacetate-forming), threo-3-hydroxyaspartate dehydratase activity 
Catalysis of the reaction: (3S)-3-hydroxy-L-aspartate = NH(4)(+) + oxaloacetate. [EC:4.3.1.16, RHEA:12427]
National Institutes of Health

Topic mentions per year

Topic mentions per year

1986-2017
01219862017

Papers overview

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2006
2006
Cloning and expression of the pyridoxal 5'-phosphate-dependent aspartate racemase gene from the bivalve mollusk Scapharca broughtonii and characterization of the recombinant enzyme.
D-aspartate is present at high concentrations in the tissues of Scapharca broughtonii, and its production depends on aspartate… (More)
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2005
2005
Dual substrate and reaction specificity in mouse serine racemase: identification of high-affinity dicarboxylate substrate and inhibitors and analysis of the beta-eliminase activity.
Mouse serine racemase (mSR) is a pyridoxal 5'-phosphate dependent enzyme that catalyzes the biosynthesis of the N-methyl-d… (More)
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1996
1996
Noise analysis of the glutamate-activated current in photoreceptors.
The glutamate-activated current in photoreceptors has been attributed both to a sodium/glutamate transporter and to a glutamate… (More)
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1996
1996
A glutamate-elicited chloride current with transporter-like properties in rod photoreceptors of the tiger salamander.
Glutamate, when puffed near the synaptic terminals, elicits a current in rod photoreceptors. The current is strongly dependent… (More)
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1995
1995
Cone photoreceptors respond to their own glutamate release in the tiger salamander.
Pulse-like currents resembling miniature postsynaptic currents were recorded in patch-clamped isolated cones from the tiger… (More)
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1995
1995
Effects of L-trans-pyrrolidine-2,4-dicarboxylate and L-threo-3-hydroxyaspartate on the binding of [3H]L-aspartate, [3H]alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate (AMPA), [3H]DL-(E)-2-amino…
L-trans-Pyrrolidine-2,4-dicarboxylate (L-t-PDC) and L-threo-3- hydroxyaspartate (L-t-3OHA), compounds known to interact strongly… (More)
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1994
1994
L-glutamate uptake inhibitors may stimulate phosphoinositide hydrolysis in baby hamster kidney cells expressing mGluR1a via heteroexchange with L-glutamate without direct activation of mGluR1a.
The functional efficacies of inhibitors of L-glutamate uptake for altering second messenger formation in baby hamster kidney… (More)
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1993
1993
Demonstration of glutamate/aspartate uptake activity in nerve endings by use of antibodies recognizing exogenous D-aspartate.
Nerve terminals as well as glial cells are thought to possess high-affinity Na(+)-dependent transport sites for excitatory amino… (More)
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1993
1993
Threonine synthase of Escherichia coli: inhibition by classical and slow-binding analogues of homoserine phosphate.
L-threo-3-Hydroxyhomoserine phosphate, derived from the antimetabolites L-threo-3-hydroxyaspartate and L-threo-3… (More)
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1986
1986
Na+-dependent "binding" of D-aspartate in brain membranes is largely due to uptake into membrane-bounded saccules.
Na+-dependent "binding" of acidic amino acids in brain plasma membranes was examined by procedures similar to those employed in… (More)
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