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thioinosinic acid

 
National Institutes of Health

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2011
2011
  • PURINETHOL mercaptopurine
  • 2011
  • Corpus ID: 1098514
Mercaptopurine (6-MP) competes with hypoxanthine and guanine for the enzyme hypoxanthineguanine phosphoribosyltransferase… Expand
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1990
1990
The colorimetric assay for 5-aminoimidazole-4-carboxamide ribotide (AICAR) transformylase (phosphoribosylamino… Expand
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1981
1981
The effect of prior administration of aminophylline, caffeine, or propranolol on the antitumor activity of 6-mercaptopurine (6-MP… Expand
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1980
1980
1 A specific assay for the measurement of thioinosinic acid, in human lymphocytes, has been developed with a sensitivity of 50 ng… Expand
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1979
1979
A series of 2'-O-acyl derivatives of 6-thioinosine cyclic 3',5'-phosphate (6-HS-cRMP) were prepared and examined for their… Expand
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1978
1978
Abstract The enhanced toxicity of 6-mercaptopurine with endotoxin has been confirmed with BALB/c male mice. Striking increases in… Expand
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1977
1977
In male BALB/c mice, a combination of individually non-lethal doses of 6-mercaptopurine and endotoxin was significantly lethal… Expand
  • table 1
  • table 2
  • table 3
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1975
1975
Leukocytes from patients with leukemia and L1210 cells from mice were examined for the rate of formation and cellular… Expand
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1972
1972
Summary The antileukemic drug, 6-mer-captopurine is cytotoxic only after it is converted to the 5′-nucleotide, thioinosinic acid… Expand
  • figure 1
  • table I
  • table 11
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1965
1965
Twenty-two different ways can be envisioned for the mode of binding of the phosphate moiety of a nucleotide to an enzyme… Expand
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