thioinosinic acid
National Institutes of Health
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To the Editor: Patients with ulcerative colitis (UC) for long periods are thought to be at high risk for developing colorectal…
The colorimetric assay for 5-aminoimidazole-4-carboxamide ribotide (AICAR) transformylase (phosphoribosylamino…
The effect of prior administration of aminophylline, caffeine, or propranolol on the antitumor activity of 6-mercaptopurine (6-MP…
A series of 2'-O-acyl derivatives of 6-thioinosine cyclic 3',5'-phosphate (6-HS-cRMP) were prepared and examined for their…
In male BALB/c mice, a combination of individually non-lethal doses of 6-mercaptopurine and endotoxin was significantly lethal…
Leukocytes from patients with leukemia and L1210 cells from mice were examined for the rate of formation and cellular…
Summary The antileukemic drug, 6-mer-captopurine is cytotoxic only after it is converted to the 5′-nucleotide, thioinosinic acid…
Twenty-two different ways can be envisioned for the mode of binding of the phosphate moiety of a nucleotide to an enzyme…