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thiamine diphosphate catabolic process

Known as: thiamin diphosphate breakdown, thiamin diphosphate degradation, thiamin diphosphate catabolism 
The chemical reactions and pathways resulting in the breakdown of thiamine diphosphate, a derivative of thiamine (vitamin B1) which acts as a… 
National Institutes of Health

Papers overview

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Highly Cited
1999
Highly Cited
1999
Remarkable stabilization of zwitterionic intermediates may account for a billion-fold rate acceleration by thiamin diphosphate-dependent decarboxylases.
When the E91D variant of apo-yeast pyruvate decarboxylase (EC 4.1.1. 1) is exposed to C2alpha-hydroxybenzylthiamin diphosphate… 
Highly Cited
1994
Highly Cited
1994
Specificity of coenzyme binding in thiamin diphosphate-dependent enzymes. Crystal structures of yeast transketolase in complex with analogs of thiamin diphosphate.
The three-dimensional structures of complexes of yeast apotransketolase with the coenzyme analogs 6'-methyl, N1'-pyridyl, and N3… 
1990
1990
Progression of neurological disease in thiamin-deficient rats is enhanced by ethanol.
1990
1990
Thiamin transport by human erythrocytes and ghosts
SummaryThiamin transport in human erythrocytes and resealed pink ghosts was evaluated by incubating both preparations at 37 or 20… 
1990
1990
High affinity of acid phosphatase encoded by PHO3 gene in Saccharomyces cerevisiae for thiamin phosphates.
1985
1985
Jejunal uptake of thiamin hydrochloride in man: influence of alcoholism and alcohol.
The jejunal uptake of 35S-thiamin hydrochloride was examined using an intestinal perfusion technique in six young students (group… 
1978
1978
Mechanism of action of the pyruvate dehydrogenase multienzyme complex from Escherichia coli.
The extent of cooperativity among the polypeptide chain components in the overall reaction catalyzed by the pyruvate… 
1977
1977
Binding of thiamin thiazolone pyrophosphate to mammalian pyruvate dehydrogenase and its effects of kinase and phosphatase activities.
Highly Cited
1976
Highly Cited
1976
Transition state analogs for thiamin pyrophosphate-dependent enzymes.
1974
1974
Regulatory properties of the pyruvate dehydrogenase complex from Escherichia coli. Studies on the thiamin diphosphate-dependent lag phase.
The pyruvate dehydrogenase complex from Escherichia coli shows an appreciable lag phase (tau) of some minutes when its overall… 
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