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thiamine diphosphate catabolic process

Known as: thiamin diphosphate breakdown, thiamin diphosphate degradation, thiamin diphosphate catabolism 
The chemical reactions and pathways resulting in the breakdown of thiamine diphosphate, a derivative of thiamine (vitamin B1) which acts as a… 
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
Nutritional inadequacies of the gluten-free diet in both recently-diagnosed and long-term patients with coeliac disease.
BACKGROUND Life-long gluten-free diet (GFD) is the only recognised treatment for coeliac disease (CD). The present study aimed to… 
Review
2013
Review
2013
Thiamin diphosphate‐dependent enzymes: from enzymology to metabolic regulation, drug design and disease models
Bringing a knowledge of enzymology into research in vivo and in situ is of great importance in understanding systems biology and… 
Highly Cited
2010
Highly Cited
2010
Chronic alcohol consumption and intestinal thiamin absorption: effects on physiological and molecular parameters of the uptake process.
Thiamin is essential for normal cellular functions, and its deficiency leads to a variety of clinical abnormalities. Humans and… 
Highly Cited
2007
Highly Cited
2007
Strain and near attack conformers in enzymic thiamin catalysis: X-ray crystallographic snapshots of bacterial transketolase in covalent complex with donor ketoses xylulose 5-phosphate and fructose 6…
Transketolase is a prominent thiamin diphosphate-dependent enzyme in sugar metabolism that catalyzes the reversible transfer of a… 
Highly Cited
2006
Highly Cited
2006
Simultaneous determination of eight water-soluble vitamins in supplemented foods by liquid chromatography.
A fast, simple, and reliable method for the isolation and determination of the vitamins thiamin, riboflavin, niacin, pantothenic… 
Highly Cited
2004
Highly Cited
2004
Kinetics of thiamin and thiamin phosphate esters in human blood, plasma and urine after 50 mg intravenously or orally
SummaryThe concentrations of thiamin and thiamin monophosphate and diphosphate in plasma and whole blood samples were assessed in… 
Highly Cited
2002
Highly Cited
2002
Impact of vitamin and mineral supplement withdrawal and wheat middling inclusion on finishing pig growth performance, fecal mineral concentration, carcass characteristics, and the nutrient content…
A study was conducted to determine if supplement withdrawal (omission of dietary vitamin and trace mineral premixes and a two… 
Highly Cited
2002
Highly Cited
2002
Targeted disruption of Slc19a2, the gene encoding the high-affinity thiamin transporter Thtr-1, causes diabetes mellitus, sensorineural deafness and megaloblastosis in mice.
Thiamin-responsive megaloblastic anemia syndrome (TRMA) is characterized by diabetes mellitus, megaloblastic anemia and… 
Highly Cited
1993
Highly Cited
1993
Thiamin and thiamin phosphate ester deficiency assessed by high performance liquid chromatography in four clinical cases of Wernicke encephalopathy.
The concentrations of thiamin and thiamin phosphate esters were determined by high performance liquid chromatography in four… 
Highly Cited
1988
Highly Cited
1988
Thiazolium C(2)-proton exchange: structure-reactivity correlations and the pKa of thiamin C(2)-H revisited.
Rate constants for C(2)-proton exchange from thiamin, N(1')-methylthiamin, and several 3-substituted-4-methylthiazolium ions… 
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