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tezosentan

Known as: 5-isopropyl-pyridine-2-sulfonic acid 6-(2-hydroxy-ethoxy)-5-(2-methoxy-phenoxy)-2-(2-1H-tetrazol-5-yl--pyridin-4-yl)--pyrimidin-4-ylamide, N-(6-(2-Hydroxyethoxy)-5-(o-methoxyphenoxy)-2-(2-(1H-tetrazol-5-yl)-4-pyridyl)-4-pyrimidinyl)-5-isopropyl-2-pyridinesulfonamide, tezosentan [Chemical/Ingredient] 
National Institutes of Health

Related topics

Related topics

5 relations

Broader (3)

PyridinesTetrazolesVasodilator Agents

Narrower (2)

RO 61-0612Veletri

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
Synthesis and Antimicrobial Activity of New Tetrazole Derivatives from 1((1H-tetrazol-5-yl) methyl)-1H- benzo(d)(1,2,3)triazole as synthon
A series of benzotriazoles and tetrazole derivatives was synthesized using 1((1H-tetrazol-5-yl) methyl)-1H- benzo(d)(1,2,3… 
2006
2006
Ischemic preconditioning prevents endothelial dysfunction, P-selectin expression, and neutrophil adhesion by preventing endothelin and O2- generation in the post-ischemic guinea-pig heart.
Evidence indicates that ischemia/reperfusion (IR) results in endothelial dysfunction and neutrophil adhesion in the post-ischemic… 
2003
2003
RANDOMIZED INTRAVENOUS TEZOSENTAN STUDY-4 INVESTIGATORS TEZOSENTAN IN PATIENTS WITH ACUTE HEART FAILURE AND ACUTE CORONARY SYNDROMES
2001
2001
Endothelin receptor blockade in congestive heart failure.
To the Editor: Of the many new therapeutic agents for slowing the progression of congestive heart failure (CHF), other than… 
2001
2001
Additional effects of endothelin receptor blockade and angiotensin converting enzyme inhibition in rats with chronic heart failure.
AIM To evaluate the acute effects of tezosentan, a new dual parenteral endothelin receptor antagonist, on hemodynamics in a rat… 
1985
1985
Anti-allergic action of 6-ethyl-3-(1H-tetrazol-5-YL) chromone (AA-344) in rats. II. Effect of AA-344 on histamine release from rat peritoneal exudate cells.
1983
1983
Quaternary heterocyclylamino beta-lactams. II. The in vitro antibacterial properties of L-640,876, a new type of beta-lactam antibiotic.
A new semisynthetic cephalosporin antibiotic designated 7-beta-(1-benzylpyridinium-4-yl)-amino-3-[( (1-methyl-1H-tetrazol-5-yl… 
1980
1980
[Studies on the absorption distribution and excretion of 14C-labelled sodium 7-[D(-)-alpha-(4-ethyl-2,3-dioxo-1-piperazine-carboxamido)-alpha-(4-hydroxyphenyl l) acetamido]-3-[(1-methyl-1H-tetrazol-5…
1979
1979
Antiallergic action of 6-ethyl-3-(1h-tetrazol-5-YL) chromone (AA-344) on immediate hypersensitivity reaction in rats.
A newly synthesized compound, 6-ethyl-3-(1H-tetrazol-5-yl)chromone (AA-344) given intravenously or orally inhibited considerably… 
1978
1978
Diastereomeric 7-ureidoacetyl cephalosporins. II. 7beta [[[(Aminocarbonyl) amino]-2-thienylacetyl] amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl) thio] methyl]-8-oxo-5-thia-1-azabicyclo [4.2.0] oct…
The synthesis and antibacterial activity in vitro of 7-methoxylated cephalosporins having a thienylureidoacetyl or a… 
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