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tensin

Known as: Tensins, Tensins [Chemical/Ingredient] 
A family of multidomain microfilament proteins that bind ACTIN FILAMENTS and INTEGRINS at FOCAL ADHESIONS. They generally consist of an N-terminal… 
National Institutes of Health

Related topics

Related topics

12 relations
Actin-Binding ProteinIn BloodProcess of secretionTNS1 gene

Narrower (2)

TNS2 protein, humanTNS4 protein, human

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2017
Review
2017
MiR-132 promotes the proliferation, invasion and migration of human pancreatic carcinoma by inhibition of the tumor suppressor gene PTEN.
Highly Cited
2010
Highly Cited
2010
17βE2 promotes cell proliferation in endometriosis by decreasing PTEN via NFκB-dependent pathway
Highly Cited
2007
Highly Cited
2007
Activation of Phosphatase and Tensin Homolog on Chromosome 10 Mediates the Inhibition of FcγR Phagocytosis by Prostaglandin E2 in Alveolar Macrophages1
PGE2 has important inhibitory effects on the macrophage host defense functions of phagocytosis and killing, yet the molecular… 
2007
2007
A chemical approach to the identification of tensin-binding proteins.
Many protein-protein interactions are mediated by small modular domains, which recognize short peptide motifs in their partner… 
Highly Cited
2006
Highly Cited
2006
Caldesmon effects on the actin cytoskeleton and cell adhesion in cultured HTM cells.
Highly Cited
2005
Highly Cited
2005
Phosphatase and Tensin Homolog Regulation of Islet Growth and Glucose Homeostasis*
The Irs2 branch of the insulin/insulin-like growth factor signaling cascade activates the phosphatidylinositol 3-kinase → Akt… 
Highly Cited
2004
Highly Cited
2004
Aerosol Delivery of Glucosylated Polyethylenimine/Phosphatase and Tensin Homologue Deleted on Chromosome 10 Complex Suppresses Akt Downstream Pathways in the Lung of K-ras Null Mice
Difficulties in achieving long-term survival of lung cancer patients treated with conventional therapies suggest that novel… 
Highly Cited
2001
Highly Cited
2001
Regulation of phosphoinositide metabolism, Akt phosphorylation, and glucose transport by PTEN (phosphatase and tensin homolog deleted on chromosome 10) in 3T3-L1 adipocytes.
To investigate the roles of PTEN (phosphatase and tensin homolog deleted on chromosome 10) in the regulation of 3-position… 
Highly Cited
1999
Highly Cited
1999
Impaired integrin-mediated signal transduction, altered cytoskeletal structure and reduced motility in Hck/Fgr deficient macrophages.
Integrin-mediated adhesion of monocytes and macrophages initiates a signal transduction pathway that leads to actin cytoskeletal… 
Highly Cited
1995
Highly Cited
1995
Molecular cloning, expression, and mapping of the high affinity actin- capping domain of chicken cardiac tensin
Tensin, an actin filament capping protein first purified from chicken gizzard, is localized to various types of adherens… 
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