tensin

Known as: Tensins, Tensins [Chemical/Ingredient] 
A family of multidomain microfilament proteins that bind ACTIN FILAMENTS and INTEGRINS at FOCAL ADHESIONS. They generally consist of an N-terminal… (More)
National Institutes of Health

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Highly Cited
2010
Highly Cited
2010
Phosphatase and tensin homolog (PTEN)-induced putative kinase 1 (PINK1) and PARK2/Parkin mutations cause autosomal recessive… (More)
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Highly Cited
2009
Highly Cited
2009
AIMS MicroRNAs (miRNAs) are small non-coding RNAs that regulate gene expression at the post-transcriptional level by either… (More)
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Highly Cited
2007
Highly Cited
2007
Cell migration driven by the epidermal growth factor receptor (EGFR) propels morphogenesis and involves reorganization of the… (More)
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Highly Cited
2007
Highly Cited
2007
The three deleted in liver cancer genes (DLC1-3) encode Rho-GTPase-activating proteins (RhoGAPs) whose expression is frequently… (More)
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Review
2006
Review
2006
The tumour-suppressor phosphatase with tensin homology (PTEN) is the most important negative regulator of the cell-survival… (More)
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Highly Cited
1998
Highly Cited
1998
PTEN is a tumor suppressor with sequence homology to protein tyrosine phosphatases and the cytoskeletal protein tensin. mPTEN… (More)
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Highly Cited
1997
Highly Cited
1997
Mapping of homozygous deletions on human chromosome 10q23 has led to the isolation of a candidate tumor suppressor gene, PTEN… (More)
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Highly Cited
1997
Highly Cited
1997
Deletions involving regions of chromosome 10 occur in the vast majority (>90%) of human glioblastoma multiformes. A region at… (More)
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Highly Cited
1994
Highly Cited
1994
Tensin, a 200-kD phosphoprotein of focal contacts, contains sequence homologies to Src (SH2 domain), and several actin-binding… (More)
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Highly Cited
1991
Highly Cited
1991
The molecular cloning of the complementary DNA coding for a 90-kilodalton fragment of tensin, an actin-binding component of focal… (More)
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