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tenilsetam

Known as: 3-(2-thienyl)piperazinone 
 
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
Advanced glycation end products (AGEs) have been identified in age-related intracellular protein deposits of Alzheimer’s disease… Expand
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Highly Cited
2007
Highly Cited
2007
Advanced glycation end products (AGEs) are found in various intraneuronal protein deposits such as neurofibrillary tangles in… Expand
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2006
2006
Hyperglycemia-induced mitochondrial overproduction of reactive oxygen species leads to the activation of different biochemical… Expand
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Review
2004
Review
2004
In Alzheimer's disease, age-related cellular changes such ascompromised energy production and increased radical formation… Expand
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Highly Cited
2001
Highly Cited
2001
The advanced glycation end-product (AGE) hypothesis proposes that accelerated chemical modification of proteins by glucose during… Expand
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Review
1998
Review
1998
Substantial evidence now exists that oxidative stress may play an important role in the etiopathogenesis of DAT. The different… Expand
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Highly Cited
1997
Highly Cited
1997
Nucleation-dependent polymerization of beta-amyloid peptide, the major component of plaques in patients with Alzheimer's disease… Expand
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Highly Cited
1997
Highly Cited
1997
It has been hypothesized that advanced Maillard reaction in vivo could explain some of the age- and diabetes-related changes… Expand
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Highly Cited
1994
Highly Cited
1994
SummaryNon-enzymatic glycosylation of proteins, also called Maillard reaction, which occurs at an accelerated rate in diabetes… Expand
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1989
1989
In a double-blind placebo-controlled study, the effects of tenilsetam, a novel antihypoxidotic/nootropic agent, on spontaneous… Expand
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