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Genomic instability has been proposed to play a role in cancer development and can occur through different… (More)
Thyroid cancer may have a familial predisposition but a specific germline alteration responsible for the disease has not been… (More)
Thyroid cancer, the commonest of endocrine malignancies, continues to increase in incidence with over 19,000 new cases… (More)
Telomeres are specialized structures at the ends of chromosomes, consisting of hundreds of repeated hexanucleotides (TTAGGG)n… (More)
Differentiated papillary thyroid cancer is mostly sporadic, but the recurrence of the familial form has been reported… (More)
- Bioorganic & medicinal chemistry letters
Telomerase and telomere maintenance are emerging targets for the treatment of human cancers. We report here on the targeting of… (More)