FAQ

telomere-telomerase complex

Known as: telomere-telomerase complex location 
A complex of DNA and protein located at the end of a linear chromosome that enables replication of the telomeric repeat sequences at the end of a… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

2004-2012
01220042012

Related topics

Related topics

1 relation

Broader (1)

chromosome, telomeric region

Related mentions per year

Related mentions per year

1992-2016
1990200020102020
telomere-telomerase complex
chromosome, telomeric region

Papers overview

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2012
2012
Telomere abnormalities and chromosome fragility in patients affected by familial papillary thyroid cancer.
INTRODUCTION Genomic instability has been proposed to play a role in cancer development and can occur through different… (More)
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2010
2010
Lack of germline A339V mutation in thyroid transcription factor-1 (TITF-1/NKX2.1) gene in familial papillary thyroid cancer
Thyroid cancer may have a familial predisposition but a specific germline alteration responsible for the disease has not been… (More)
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Review
2010
Review
2010
Familial nonmedullary thyroid cancer: a review of the genetics.
OBJECTIVE Thyroid cancer, the commonest of endocrine malignancies, continues to increase in incidence with over 19,000 new cases… (More)
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Review
2009
Review
2009
Telomeres and Thyroid Cancer
Telomeres are specialized structures at the ends of chromosomes, consisting of hundreds of repeated hexanucleotides (TTAGGG)n… (More)
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2008
2008
Short telomeres, telomerase reverse transcriptase gene amplification, and increased telomerase activity in the blood of familial papillary thyroid cancer patients.
BACKGROUND Differentiated papillary thyroid cancer is mostly sporadic, but the recurrence of the familial form has been reported… (More)
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2004
2004
Synthesis, biophysical and biological evaluation of 3,6-bis-amidoacridines with extended 9-anilino substituents as potent G-quadruplex-binding telomerase inhibitors.
Telomerase and telomere maintenance are emerging targets for the treatment of human cancers. We report here on the targeting of… (More)
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