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taxadiene 5-alpha-hydroxylase activity

Known as: taxa-4,11-diene,hydrogen-donor:oxygen oxidoreductase (5alpha-hydroxylating), taxadiene 5a-hydroxylase activity, taxadiene 5alpha-hydroxylase activity 
Catalysis of the reaction: AH(2) + O(2) + taxa-4,11-diene = A + H(2)O + taxa-4(20),11-dien-5alpha-ol. [EC:1.14.99.37, RHEA:14052]
National Institutes of Health

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1999
1999
The systematic investigation on the roots of Taxus wallichiana has resulted in the isolation of nine taxoids-taxol 1 baccatin III…