tasisulam

Known as: N-(2,4-Dichlorobenzoyl)-5-bromothiophene-2-sulfonamide 
An acyl-sulfonamide with potential antineoplastic activity. Selectively toxic towards tumor cells, tasisulam appears to induce tumor cell apoptosis… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

2011-2016
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Papers overview

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2017
2017
Cytochrome P450 2C9 (CYP2C9) is involved in the biotransformation of many commonly used drugs, and significant drug interactions… (More)
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2014
2014
Background This phase Ib study used a parallel, multi-arm design to examine tasisulam-sodium (hereafter tasisulam), a drug with… (More)
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2013
2013
This phase I study was designed to determine the maximum tolerated dose (MTD) and the dose to be recommended for a future phase… (More)
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2012
2012
INTRODUCTION Tasisulam sodium (hereafter referred to as tasisulam) is a novel anticancer compound that induces apoptosis and… (More)
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2012
2012
114 Background: Tasisulam, a novel acylsulfonamide antineoplastic agent, promotes apoptosis, exhibits antiangiogenic activities… (More)
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2012
2012
Background Tasisulam sodium (hereafter tasisulam), a novel anticancer agent, is being studied in a broad range of tumors. The… (More)
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2012
2012
Primary melanoma of the urinary bladder is a rare subentity of melanoma. The same applies for melanoma of the rhabdoid… (More)
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2011
2011
LY573636-sodium (tasisulam) is a small molecule antitumor agent with a novel mechanism of action currently being investigated in… (More)
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2011
2011
BACKGROUND Tasisulam sodium (hereafter, tasisulam) is a novel anticancer agent that induces apoptosis through the intrinsic… (More)
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2011
2011
This phase I study was carried out to determine the phase II recommended dose of tasisulam sodium (hereafter, tasisulam), a novel… (More)
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