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tasidotin

A third generation, synthetic, water-soluble, pentapeptide analog of the marine depsipeptide dolastatin 15, with potential antimitotic and… 
National Institutes of Health

Papers overview

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2019
2019
This work presents an account of the reactivity behavior of the anticancer marine drugs, Soblidotin and Tasidotin, based on the… 
Review
2018
Review
2018
Microalgae are one of the oldest microorganisms, that grow in various hostile environments, ranging from deserts to Antarctica… 
Review
2015
Review
2015
The use of synthetic anticancer drugs and other methods followed in cancer therapy have several side effects; and ineffective… 
2013
2013
  • M. Lopus
  • Molecular and Cellular Biochemistry
  • 2013
  • Corpus ID: 12268937
Dolastatin 15 (DL15) is a potent, tubulin-targeted, vinca-site binding, anticancer agent that induces mitotic arrest and inhibit… 
2009
2009
Tasidotin, an oncolytic drug in phase II clinical trials, is a peptide analog of the antimitotic depsipeptide dolastatin 15. In… 
2009
2009
PurposeThe dynamic instability of microtubules in cells is one of the key targets of anticancer therapeutics. Microtubule… 
2007
2007
Tasidotin (ILX-651), an orally active synthetic microtubule-targeted derivative of the marine depsipeptide dolastatin-15, is… 
2005
2005
Purpose: To determine the maximum tolerated dose, dose-limiting toxicity, and pharmacokinetics of the dolastatin-15 analogue… 
2005
2005
Purpose: To determine the maximum tolerated dose (MTD), dose-limiting toxicity (DLT), and pharmacokinetics of tasidotin (ILX651… 
Review
2005
Review
2005