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tasidotin
A third generation, synthetic, water-soluble, pentapeptide analog of the marine depsipeptide dolastatin 15, with potential antimitotic and…
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National Institutes of Health
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Related topics
Related topics
5 relations
Narrower (2)
ILX 651
tasidotin hydrochloride
Microtubule Process
NCIt Antineoplastic Agent Terminology
Broader (1)
Oligopeptides
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2005
2005
Phase I and Pharmacokinetic Study of the Dolastatin-15 Analogue Tasidotin (ILX651) Administered Intravenously on Days1, 3, and 5 Every 3 Weeks in Patientswith Advanced Solid Tumors
C. Cunningham
,
L. Appleman
,
+10 authors
J. Eder
2005
Corpus ID: 15395818
Purpose: To determine the maximum tolerated dose (MTD), dose-limiting toxicity (DLT), and pharmacokinetics of tasidotin (ILX651…
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2005
2005
APhase I Study of the Dolastatin-15 Analogue Tasidotin (ILX651) Administered Intravenously Daily for 5 Consecutive Days Every 3Weeks in Patientswith Advanced SolidTumors
S. Ebbinghaus
,
E. Rubin
,
+6 authors
L. Hammond
2005
Corpus ID: 40793889
Purpose:To determine themaximum tolerated dose, dose-limiting toxicity, andpharmacokinetics of the dolastatin-15 analogue…
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2005
2005
In vivo antitumor effect of Tasidotin HCl (formerly ILX651), a dolastatin-15 analog with a novel mechanism of action, against the PANC-1 and MiaPaCa human pancreatic tumor xenograft models
L. Arthaud
,
Stephanie D. Roth
,
Roy D. Krumbholz
,
S. Weitman
2005
Corpus ID: 199615804
5904 Tasidotin HCl is a synthetic pentapeptide derivative of dolastatin-15 with a unique mechanism of action that potentially…
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