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Eighteen analogues of the marine cytotoxic linear peptide tasiamide were designed, synthesized and screened for their inhibitory… Expand A collection of the tropical marine cyanobacterium Symploca sp., collected near Kimbe Bay, Papua New Guinea, previously yielded… Expand Marine blue green algae are among the most primitive life forms on earth. These simple prokaryotes have not only the ability to… Expand The total synthesis of a marine acyclic peptide tasiamide and three diastereomers was reported for the first time. The synthesis… Expand The Japan-China Joint Medical Workshop on Drug Discoveries and Therapeutics 2008 (JCMWDDT 2008) was held from September 29 to… Expand The acyclic peptide tasiamide (1) has been isolated from the marine cyanobacterium Symploca sp. The planar structure and absolute… Expand