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talin binding

Interacting selectively and non-covalently with a talin, a family of related cytoskeletal proteins that play a role in assembly of actin filaments… Expand
National Institutes of Health

Papers overview

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2019
2019
Integrins and integrin-dependent cell-matrix adhesions are essential for a number of physiological processes. Integrin function… Expand
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2017
2017
Kidney collecting system development requires integrin-dependent cell-extracellular matrix interactions. Integrins are… Expand
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2015
2015
In this issue of Blood , Klapproth et al used mice that were hypomorphic for the protein kindlin-3 to demonstrate that as little… Expand
2014
2014
Abstract The αIIb cytoplasmic domain of platelet integrin αIIbβ3 contains an unorganized acidic membrane-distal 1000LEEDDEEGE1008… Expand
Highly Cited
2012
Highly Cited
2012
Talin binding to the integrin β tail alters the β transmembrane domain’s topology, resulting in integrin activation. 
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Highly Cited
2009
Highly Cited
2009
Rap1 small GTPases interact with Rap1-GTP-interacting adaptor molecule (RIAM), a member of the MRL (Mig-10/RIAM/Lamellipodin… Expand
Highly Cited
2009
Highly Cited
2009
links to actin. Talin binding is also crucial in the conversion of low-affinity to high-affinity integrins (14) and in the… Expand
Highly Cited
2008
Highly Cited
2008
Integrins play a fundamental role in cell migration and adhesion; knowledge of how they are regulated and controlled is vital for… Expand
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Highly Cited
2001
Highly Cited
2001
Talin links integrin beta cytoplasmic domains to the actin cytoskeleton and is involved in the clustering and activation of these… Expand
Highly Cited
1989
Highly Cited
1989
Binding of the cytoskeletal protein vinculin to talin is one of a number of interactions involved in linking F-actin to cell… Expand
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