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talin binding

Interacting selectively and non-covalently with a talin, a family of related cytoskeletal proteins that play a role in assembly of actin filaments… 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Clustering of integrin β cytoplasmic domains triggers nascent adhesion formation and reveals a protozoan origin of the integrin-talin interaction
Integrins and integrin-dependent cell-matrix adhesions are essential for a number of physiological processes. Integrin function… 
2017
2017
Talin regulates integrin β1-dependent and -independent cell functions in ureteric bud development
Kidney collecting system development requires integrin-dependent cell-extracellular matrix interactions. Integrins are… 
2015
2015
Comment on Klapproth et al , page 2592 A little bit of kindlin goes a long
In this issue of Blood, Klapproth et al used mice that were hypomorphic for the protein kindlin-3 to demonstrate that as little… 
2014
2014
Palmitoylated peptide, being derived from the carboxyl-terminal sequence of the integrin αIIb cytoplasmic domain, inhibits talin binding to αIIbβ3
Abstract The αIIb cytoplasmic domain of platelet integrin αIIbβ3 contains an unorganized acidic membrane-distal 1000LEEDDEEGE1008… 
Highly Cited
2012
Highly Cited
2012
Talin activates integrins by altering the topology of the β transmembrane domain
Talin binding to the integrin β tail alters the β transmembrane domain’s topology, resulting in integrin activation. 
Highly Cited
2009
Highly Cited
2009
RIAM Activates Integrins by Linking Talin to Ras GTPase Membrane-targeting Sequences*
Rap1 small GTPases interact with Rap1-GTP-interacting adaptor molecule (RIAM), a member of the MRL (Mig-10/RIAM/Lamellipodin… 
Highly Cited
2009
Highly Cited
2009
Transforming Graphene
links to actin. Talin binding is also crucial in the conversion of low-affinity to high-affinity integrins (14) and in the… 
Highly Cited
2008
Highly Cited
2008
An Integrin Phosphorylation Switch
Integrins play a fundamental role in cell migration and adhesion; knowledge of how they are regulated and controlled is vital for… 
Highly Cited
2001
Highly Cited
2001
Calpain cleavage promotes talin binding to the beta 3 integrin cytoplasmic domain.
Talin links integrin beta cytoplasmic domains to the actin cytoskeleton and is involved in the clustering and activation of these… 
Highly Cited
1989
Highly Cited
1989
Identification of a talin binding site in the cytoskeletal protein vinculin
Binding of the cytoskeletal protein vinculin to talin is one of a number of interactions involved in linking F-actin to cell… 
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