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talin binding
Interacting selectively and non-covalently with a talin, a family of related cytoskeletal proteins that play a role in assembly of actin filaments…
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National Institutes of Health
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Clustering of integrin β cytoplasmic domains triggers nascent adhesion formation and reveals a protozoan origin of the integrin-talin interaction
Timo Baade
,
Christoph Paone
,
Adrian Baldrich
,
C. Hauck
Scientific Reports
2019
Corpus ID: 96449427
Integrins and integrin-dependent cell-matrix adhesions are essential for a number of physiological processes. Integrin function…
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2017
2017
Talin regulates integrin β1-dependent and -independent cell functions in ureteric bud development
S. Mathew
,
Riya J. Palamuttam
,
+10 authors
R. Zent
Development
2017
Corpus ID: 207161955
Kidney collecting system development requires integrin-dependent cell-extracellular matrix interactions. Integrins are…
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2015
2015
Comment on Klapproth et al , page 2592 A little bit of kindlin goes a long
J. Bennett
2015
Corpus ID: 30415622
In this issue of Blood, Klapproth et al used mice that were hypomorphic for the protein kindlin-3 to demonstrate that as little…
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2014
2014
Palmitoylated peptide, being derived from the carboxyl-terminal sequence of the integrin αIIb cytoplasmic domain, inhibits talin binding to αIIbβ3
A. Gkourogianni
,
M. Egot
,
+6 authors
D. Tsoukatos
Platelets
2014
Corpus ID: 25098467
Abstract The αIIb cytoplasmic domain of platelet integrin αIIbβ3 contains an unorganized acidic membrane-distal 1000LEEDDEEGE1008…
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Highly Cited
2012
Highly Cited
2012
Talin activates integrins by altering the topology of the β transmembrane domain
Chungho Kim
,
F. Ye
,
Xiaohui Hu
,
M. Ginsberg
The Journal of cell biology
2012
Corpus ID: 12003787
Talin binding to the integrin β tail alters the β transmembrane domain’s topology, resulting in integrin activation.
Highly Cited
2009
Highly Cited
2009
RIAM Activates Integrins by Linking Talin to Ras GTPase Membrane-targeting Sequences*
Ho-Sup Lee
,
C. Lim
,
W. Puzon‐McLaughlin
,
S. Shattil
,
M. Ginsberg
Journal of Biological Chemistry
2009
Corpus ID: 30069816
Rap1 small GTPases interact with Rap1-GTP-interacting adaptor molecule (RIAM), a member of the MRL (Mig-10/RIAM/Lamellipodin…
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Highly Cited
2009
Highly Cited
2009
Transforming Graphene
A. Savchenko
Science
2009
Corpus ID: 206517748
links to actin. Talin binding is also crucial in the conversion of low-affinity to high-affinity integrins (14) and in the…
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Highly Cited
2008
Highly Cited
2008
An Integrin Phosphorylation Switch
Camilla L. Oxley
,
Nicholas J Anthis
,
E. Lowe
,
I. Vakonakis
,
I. Campbell
,
L. Wegener
Journal of Biological Chemistry
2008
Corpus ID: 38827911
Integrins play a fundamental role in cell migration and adhesion; knowledge of how they are regulated and controlled is vital for…
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Highly Cited
2001
Highly Cited
2001
Calpain cleavage promotes talin binding to the beta 3 integrin cytoplasmic domain.
B. Yan
,
D. Calderwood
,
B. Yaspan
,
M. Ginsberg
The Journal of biological chemistry
2001
Corpus ID: 30772677
Talin links integrin beta cytoplasmic domains to the actin cytoskeleton and is involved in the clustering and activation of these…
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Highly Cited
1989
Highly Cited
1989
Identification of a talin binding site in the cytoskeletal protein vinculin
P. Jones
,
P. Jackson
,
+4 authors
D. Critchley
The Journal of cell biology
1989
Corpus ID: 2074801
Binding of the cytoskeletal protein vinculin to talin is one of a number of interactions involved in linking F-actin to cell…
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