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talin binding

Interacting selectively and non-covalently with a talin, a family of related cytoskeletal proteins that play a role in assembly of actin filaments… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Clustering of integrin β cytoplasmic domains triggers nascent adhesion formation and reveals a protozoan origin of the integrin-talin interaction
Integrins and integrin-dependent cell-matrix adhesions are essential for a number of physiological processes. Integrin function… Expand
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2017
2017
Talin regulates integrin β1-dependent and -independent cell functions in ureteric bud development.
Kidney collecting system development requires integrin-dependent cell-extracellular matrix interactions. Integrins are… Expand
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2015
2015
A little bit of kindlin goes a long way.
In this issue of Blood , Klapproth et al used mice that were hypomorphic for the protein kindlin-3 to demonstrate that as little… Expand
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2015
2015
Comment on Klapproth et al , page 2592 A little bit of kindlin goes a long
In this issue of Blood, Klapproth et al used mice that were hypomorphic for the protein kindlin-3 to demonstrate that as little… Expand
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2014
2014
Palmitoylated peptide, being derived from the carboxyl-terminal sequence of the integrin αIIb cytoplasmic domain, inhibits talin binding to αIIbβ₃.
The αIIb cytoplasmic domain of platelet integrin αIIbβ3 contains an unorganized acidic membrane-distal (1000)LEEDDEEGE(1008… Expand
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2012
2012
Talin activates integrins by altering the topology of the β transmembrane domain
Talin binding to integrin β tails increases ligand binding affinity (activation). Changes in β transmembrane domain (TMD… Expand
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Highly Cited
2009
Highly Cited
2009
RIAM activates integrins by linking talin to ras GTPase membrane-targeting sequences.
Rap1 small GTPases interact with Rap1-GTP-interacting adaptor molecule (RIAM), a member of the MRL (Mig-10/RIAM/Lamellipodin… Expand
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Highly Cited
2008
Highly Cited
2008
An integrin phosphorylation switch: the effect of beta3 integrin tail phosphorylation on Dok1 and talin binding.
Integrins play a fundamental role in cell migration and adhesion; knowledge of how they are regulated and controlled is vital for… Expand
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Highly Cited
2001
Highly Cited
2001
Calpain cleavage promotes talin binding to the beta 3 integrin cytoplasmic domain.
Talin links integrin beta cytoplasmic domains to the actin cytoskeleton and is involved in the clustering and activation of these… Expand
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1989
1989
Identification of a talin binding site in the cytoskeletal protein vinculin
Binding of the cytoskeletal protein vinculin to talin is one of a number of interactions involved in linking F-actin to cell… Expand
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