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substance P degrading enzyme

Known as: SPD enzyme, substance P endopeptidase 
National Institutes of Health

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Broader (1)

Metalloendopeptidases

Papers overview

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2006
2006
Chromatographic characterization of substance P endopeptidase in the rat brain reveals affected enzyme activity following heat stress.
This paper describes a study of substance P endopeptidase (SPE)-like activity in various regions of the brain from male rats… 
2001
2001
The Impact of Substance P (SP) N-Terminal Metabolite SP1-7 in Opioid Tolerance and Withdrawal
The heptapeptide SP1-7, a metabolite of the neuroactive peptide substance P (SP), is suggested to play a role in opioid addiction… 
1997
1997
Elevated cerebrospinal fluid level of substance P and decreased undecapeptidase activity at term pregnancy
1996
1996
Neuropeptide-converting enzymes in cerebrospinal fluid: activities increased in pain from herniated lumbar dis, but not from coxarthrosis.
We measured activities of dynorphin-converting enzyme (DCE), substance P endopeptidase (SPE) and angiotensin-converting enzyme… 
1992
1992
Decreased neuropeptide-converting enzyme activities in cerebrospinal fluid during acute but not chronic phases of collagen induced arthritis in rats
1992
1992
Decreased cerebrospinal fluid neuropeptide-converting enzyme activity in monoarthritic rats
1990
1990
Neuropeptide converting enzyme activities in CSF of low back pain patients
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