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stubomycin
Known as:
Cyclopent(i)azacyclononadecine-7,17(8H,19H)-dione, 9,10,13,14,15,16,20,20a-octahydro-15,18-dihydroxy-19-methoxy-2-methyl-9-phenyl-
, hitachimycin
National Institutes of Health
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Two inhibitors of yeast plasma membrane ATPase 1 (ScPma1p): toward the development of novel antifungal therapies
S. Ottilie
,
G. Goldgof
,
+7 authors
Jacob D. Durrant
Journal of Cheminformatics
2018
Corpus ID: 3393568
Given that many antifungal medications are susceptible to evolved resistance, there is a need for novel drugs with unique…
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2015
2015
Genome Mining of the Hitachimycin Biosynthetic Gene Cluster: Involvement of a Phenylalanine‐2,3‐aminomutase in Biosynthesis
F. Kudo
,
K. Kawamura
,
+4 authors
T. Eguchi
Chembiochem : a European journal of chemical…
2015
Corpus ID: 44391221
Hitachimycin is a macrolactam antibiotic with (S)‐β‐phenylalanine (β‐Phe) at the starter position of its polyketide skeleton. To…
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2004
2004
Streptomyces scabrisporus sp. nov.
X. Ping
,
Yōko Takahashi
,
A. Seino
,
Y. Iwai
,
S. Ōmura
International journal of systematic and…
2004
Corpus ID: 25073993
The taxonomic position was determined for a soil actinomycete, isolate KM-4927(T), that produced the antibiotic hitachimycin. The…
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1989
1989
Chemical modification of hitachimycin. II. Synthesis and antitumor activities of carbonate derivatives.
K. Shibata
,
S. Satsumabayashi
,
+4 authors
S. Ōmura
The Journal of antibiotics
1989
Corpus ID: 27274810
Several carbonate derivatives of hitachimycin have been synthesized and evaluated their activities including antibacterial…
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1989
1989
Hitachimycin (a.k.a. stubomycin): structural and synthetic studies
Amos B. Smith
1989
Corpus ID: 94350873
Abstract
1988
1988
Chemical modification of hitachimycin. Synthesis, antibacterial, cytocidal and in vivo antitumor activities of hitachimycin derivatives.
K. Shibata
,
S. Satsumabayashi
,
H. Sano
,
K. Komiyama
,
A. Nakagawa
,
S. Ōmura
The Journal of antibiotics
1988
Corpus ID: 32864457
Several acyl derivatives of hitachimycin have been synthesized and their activities, including antibacterial, cytocidal against…
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1985
1985
Mechanism of action of antitumor antibiotic stubomycin.
K. Komiyama
,
K. Iwasaki
,
M. Miura
,
H. Yamamoto
,
Y. Nozawa
,
I. Umezawa
The Journal of antibiotics
1985
Corpus ID: 1770258
Stubomycin, a macrocyclic lactam involving jS-phenylalanine, has been shown to have marked antitumor activity on several kinds of…
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1983
1983
Studies on the biological activity of stubomycin.
K. Komiyama
,
K. Edanami
,
A. Tanoh
,
H. Yamamoto
,
I. Umezawa
The Journal of antibiotics
1983
Corpus ID: 37700619
Stubomycin showed direct cytotoxic activity on mammalian cells, yeast, and fungi, and rapid hemolytic activity on mouse…
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1982
1982
Antitumor activity of a new antitumor antibiotic, stubomycin.
K. Komiyama
,
K. Edanami
,
H. Yamamoto
,
I. Umezawa
The Journal of antibiotics
1982
Corpus ID: 14375457
The antitumor activity of a new antibiotic, stubomycin, against various murine tumors was studied. Stubomycin showed antitumor…
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1981
1981
A new antitumor antibiotic, stubomycin.
I. Umezawa
,
H. Takeshima
,
K. Komiyama
,
Y. Koh
,
H. Yamamoto
,
M. Kawaguchi
The Journal of antibiotics
1981
Corpus ID: 21902824
A new antibiotic, stubomycin, was isolated from the culture broth and mycelia of Streptomyces strain No. KG-2245. Stubomycin was…
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