FAQ

sterol response element binding

Known as: SRE binding 
Interacting selectively and non-covalently with the sterol response element (SRE), a nonpalindromic sequence found in the promoters of genes involved… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1992-2018
0246819922018

Papers overview

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2015
2015
miR-122 Regulates LH Receptor Expression by Activating Sterol Response Element Binding Protein in Rat Ovaries.
LH/human chorionic gonadotropin receptor (LHR) undergoes down-regulation during preovulatory LH surge or in response to exposure… (More)
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2010
2010
Regulation of the ADMA-DDAH system in endothelial cells: a novel mechanism for the sterol response element binding proteins, SREBP1c and -2.
Asymmetric dimethylarginine (ADMA) has been implicated in the progression of cardiovascular disease as an endogenous inhibitor of… (More)
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Highly Cited
2010
Highly Cited
2010
Strong induction of PCSK9 gene expression through HNF1alpha and SREBP2: mechanism for the resistance to LDL-cholesterol lowering effect of statins in dyslipidemic hamsters.
We investigated the role of proprotein convertase subtilisin/kexin type 9 (PCSK9) in the resistance of dyslipidemic hamsters to… (More)
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Highly Cited
2007
Highly Cited
2007
Cideb regulates diet-induced obesity, liver steatosis, and insulin sensitivity by controlling lipogenesis and fatty acid oxidation.
OBJECTIVE Our previous study suggests that Cidea, a member of Cide family proteins that share sequence homology with the DNA… (More)
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Highly Cited
2006
Highly Cited
2006
Predominant role of sterol response element binding proteins (SREBP) lipogenic pathways in hepatic steatosis in the murine intragastric ethanol feeding model.
BACKGROUND/AIMS Alcohol-induced fatty liver is associated with induction of sterol response element binding proteins (SREBPs… (More)
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Highly Cited
2003
Highly Cited
2003
Promoter-specific roles for liver X receptor/corepressor complexes in the regulation of ABCA1 and SREBP1 gene expression.
Liver X receptors (LXRs) regulate the expression of genes involved in cholesterol and fatty acid homeostasis, including the genes… (More)
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Highly Cited
2002
Highly Cited
2002
A novel interaction between lamin A and SREBP1: implications for partial lipodystrophy and other laminopathies.
The gene encoding nuclear lamins A and C is mutated in at least three inherited disorders. Two of these, Emery-Dreifuss muscular… (More)
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2002
2002
Insulin-stimulated fatty acid synthase gene expression does not require increased sterol response element binding protein 1 transcription in primary adipocytes.
Sterol response element binding protein 1c (SREBP-1c) is a transcription factor that has been implicated in the regulation of… (More)
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Highly Cited
1999
Highly Cited
1999
Essential role in vivo of upstream stimulatory factors for a normal dietary response of the fatty acid synthase gene in the liver.
In the liver, transcription of several genes encoding lipogenic and glycolytic enzymes, in particular the gene for fatty acid… (More)
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1997
1997
Coordinate regulation of lipogenesis, the assembly and secretion of apolipoprotein B-containing lipoproteins by sterol response element binding protein 1.
Stable plasmid-driven expression of the liver-specific gene product cholesterol 7alpha-hydroxylase (7alpha-hydroxylase) was used… (More)
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