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squamosamide

Known as: Benzeneacetamide, 4-hydroxy-alpha-((4-hydroxy-3-methoxyphenyl)methylene)-N-(2-(4-hydroxyphenyl)ethyl)-3,5-dimethoxy-, (E)- 
National Institutes of Health

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3 relations

Broader (2)

BenzeneacetamidesPhenols

Narrower (1)

FLZ compound

Papers overview

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2015
2015
FLZ attenuates learning and memory deficits via suppressing neuroinflammation induced by LPS in mice
Alzheimer's disease (AD) is the most common neurodegenerative disorder in which neuroinflammation plays an important role. FLZ is… 
2015
2015
Squamosamide Derivative FLZ Protects Pancreatic β-Cells from Glucotoxicity by Stimulating Akt-FOXO1 Pathway
Chronic hyperglycemia increases apoptosis and reduces glucose-stimulated insulin secretion. Although protective agents have been… 
2013
2013
[Therapeutic effect of a natural squamosamide derivative FLZ on Parkinson's disease model mice induced by LPS plus MPTP].
The aim of this study is to investigate the protective effect of N-[2-(4-hydroxyphenyl)ethyl]-2-(2, 5-dimethoxyphenyl)-3-(3… 
2011
2011
Anti-proliferative effects of the novel squamosamide derivative (FLZ) on HepG2 human hepatoma cells by regulating the cell cycle-related proteins are associated with decreased Ca(2+)/ROS levels.
2009
2009
A natural squamosamide derivative FLZ reduces amyloid-beta production by increasing non-amyloidogenic AbetaPP processing.
Substantial evidence supports a central role of Abeta in the pathogenesis of Alzheimer's disease (AD). We have demonstrated that… 
2008
2008
Novel squamosamide derivative (compound FLZ) attenuates Aβ25–35-induced toxicity in SH-SY5Y cells
AbstractAim:The aim of the present study was to investigate the protective effect of compound N-[2-(4-hydroxy-phenyl)-ethyl]-2-(2… 
2006
2006
Protective effects of compound FLZ on β-amyloid peptide-(25–35)-induced mouse hippocampal injury and learning and memory impairment
AbstractAim:To study the protective effects of compound FLZ, a novel synthetic analogue of natural squamosamide, on learning and… 
1993
1993
[Studies on total synthesis of squamosamide].
A new natural compound squamosamide isolated from Annona squamosa, was synthesized. This compound was characterized by 1H, 13CNMR… 
1993
1993
Studies on total synthesis of squamosamide
A new natural compound squamosamide isolated from Annona squamosa,was synthesized. This compound was characterized by ~1H, ~(13… 
1992
1992
[Studies on the chemical constituents of Annona squamosa].
Twelve compounds were isolated from Annona squamosa. Their structures were identified as liriodenine (AS-1), moupinamide (AS-2… 
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