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spiruchostatin A

 
National Institutes of Health

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2012
2012
Idiopathic pulmonary fibrosis (IPF) is a progressive scarring disorder characterized by the proliferation of interstitial… Expand
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2009
2009
HDAC inhibitor Spiruchostatin A was synthesized via a route that differs significantly from previously reported routes. The key… Expand
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2008
2008
We recently completed the total synthesis of spiruchostatin A, a depsipeptide natural product with close structural similarities… Expand
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2005
2005
Anacardic acid is an alkylsalicylic acid obtained from cashew-nut-shell liquid, and is a potent inhibitor of p300 histone acetyl… Expand
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2004
2004
The total synthesis of spiruchostatin A was accomplished, unambiguously confirming its structure. Key steps included the use of… Expand
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2004
2004
Histone deacetylases are enzymes involved in regulating DNA transcription, and several molecules that inhibit their activity are… Expand
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