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spirastrellolide A methyl ester

 
National Institutes of Health

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spirastrellolide A

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2012
2012
The stereocontrolled total synthesis of spirastrellolide A methyl ester. Fragment coupling studies and completion of the synthesis.
The spirastrellolides are a novel family of structurally unprecedented marine macrolides which show promising anticancer… Expand
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2012
2012
The stereocontrolled total synthesis of spirastrellolide A methyl ester. Expedient construction of the key fragments.
Due to a combination of their promising anticancer properties, limited supply from the marine sponge source and their… Expand
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2008
2008
Total synthesis of spirastrellolide A methyl ester--part 2: Subunit union and completion of the synthesis.
The marine macrolide spirastrellolide A (1, Scheme 1) is a potent and selective protein phosphatase inhibitor, causing premature… Expand
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