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species difference

 
National Institutes of Health

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1 relation
Science of genetics

Papers overview

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2017
2017
Interspecies comparison of the functional characteristics of plasma membrane monoamine transporter (PMAT) between human, rat and mouse
Plasma membrane monoamine transporter (PMAT) is a newly discovered monoamine transporter belonging to the equilibrative… Expand
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2017
2017
Stereoselective protein binding studies of 2-(2-hydroxypropanamido) benzoic acid enantiomers in rat, beagle dog and human plasma.
As the stereoselective plasma protein binding is an important factor for the differences in pharmacokinetic or pharmacodynamic… Expand
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Review
2017
Review
2017
The role of carbonyl reductase 1 in drug discovery and development
  • S. M. Shi, Li Di
  • Expert opinion on drug metabolism & toxicology
  • 2017
    • Corpus ID: 205908530
ABSTRACT Introduction: Carbonyl reductase 1 (CBR1) plays a critical role in drug metabolism of ketones and aldehydes. CBR1 has… Expand
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2016
2016
Mechanism of Developmental Effects in Rats Caused by an N-Phenylimide Herbicide: Transient Fetal Anemia and Sequelae during Mid-to-Late Gestation.
BACKGROUND Rat developmental toxicity including embryolethality and teratogenicity (mainly ventricular septal defects [VSDs] and… Expand
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2013
2013
Transport of Kynurenic Acid by Rat Organic Anion Transporters rOAT1 and rOAT3: Species Difference between Human and Rat in OAT1
A tryptophan catabolite, kynurenic acid, is involved in schizophrenia and uremia; there is little information on the mechanism of… Expand
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2013
2013
Human mannose-binding lectin 2 is directly regulated by peroxisome proliferator-activated receptors via a peroxisome proliferator responsive element.
Human mannose-binding lectin (MBL) is encoded by the MBL2 gene and is a key player in innate immunity. However, the mechanism of… Expand
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