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species difference

 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2013-2017
012320132017

Related topics

Related topics

1 relation
Science of genetics

Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
species difference
Science of genetics

Papers overview

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2018
2018
Aldehyde oxidase-dependent species difference in hepatic metabolism of fasudil to hydroxyfasudil.
1. An investigation on the metabolic mechanism of fasudil to hydroxyfasudil was conducted in vitro using liver subcellular… (More)
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2017
2017
Identification of UDP-glucuronosyltransferases 1A1, 1A3 and 2B15 as the main contributors to glucuronidation of bakuchiol, a natural biologically active compound.
1. Bakuchiol, one of the main active compounds of Psoralea corylifolia, possesses a variety of pharmacological activities such as… (More)
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2017
2017
Interspecies comparison of the functional characteristics of plasma membrane monoamine transporter (PMAT) between human, rat and mouse.
Plasma membrane monoamine transporter (PMAT) is a newly discovered monoamine transporter belonging to the equilibrative… (More)
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Review
2017
Review
2017
The role of carbonyl reductase 1 in drug discovery and development.
INTRODUCTION Carbonyl reductase 1 (CBR1) plays a critical role in drug metabolism of ketones and aldehydes. CBR1 has broad… (More)
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2016
2016
Quantitative analysis of total serum glycome in human and mouse.
Model mice are frequently used in drug discovery research. Knowledge of similarities and differences between the mouse and human… (More)
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2016
2016
Mechanism of Developmental Effects in Rats Caused by an N-Phenylimide Herbicide: Transient Fetal Anemia and Sequelae during Mid-to-Late Gestation.
BACKGROUND Rat developmental toxicity including embryolethality and teratogenicity (mainly ventricular septal defects [VSDs] and… (More)
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2015
2015
Method development for the determination of D- and L-isomers of leucine in human plasma by high-performance liquid chromatography tandem mass spectrometry and its application to animal plasma samples…
We developed a highly sensitive and specific high-performance liquid chromatography tandem mass spectrometry method with an… (More)
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2014
2014
Activation of the constitutive androstane receptor inhibits gluconeogenesis without affecting lipogenesis or fatty acid synthesis in human hepatocytes.
OBJECTIVE Accumulating evidence suggests that activation of mouse constitutive androstane receptor (mCAR) alleviates type 2… (More)
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2013
2013
Transport of Kynurenic Acid by Rat Organic Anion Transporters rOAT1 and rOAT3: Species Difference between Human and Rat in OAT1
A tryptophan catabolite, kynurenic acid, is involved in schizophrenia and uremia; there is little information on the mechanism of… (More)
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2013
2013
Human mannose-binding lectin 2 is directly regulated by peroxisome proliferator-activated receptors via a peroxisome proliferator responsive element.
Human mannose-binding lectin (MBL) is encoded by the MBL2 gene and is a key player in innate immunity. However, the mechanism of… (More)
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