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sorivudine
Known as:
5-(2-bromovinyl)-1-beta-D- arabinofuranosyluracil
, 2,4(1H,3H)-Pyrimidinedione, 1-beta-D-arabinofuranosyl-5-(2-bromoethenyl)-, (E)-
, 1-beta-D-arabinofuranosyl-5-(2-bromovinyl)uracil
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A synthetic thymidine analogue with potent antiviral activity against herpes simplex and varicella zoster viruses. Sorivudine is phosphorylated into…
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National Institutes of Health
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Related topics
Related topics
4 relations
Broader (2)
Antiviral Agents
Arabinofuranosyluracil
Narrower (1)
YN-72
analogs & derivatives
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
IT-30ReACT: A PHASE II STUDY OF RINDOPEPIMUT VACCINE (CDX-110) PLUS BEVACIZUMAB IN RELAPSED GLIOBLASTOMA
D. Reardon
,
J. Schuster
,
+13 authors
J. Sampson
2014
Corpus ID: 76584854
BACKGROUND: EGFRvIII, a constitutively active tumorigenic EGFR deletion mutation, is linked to poor long-term survival. The…
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2008
2008
Antimicrobial Agents and Chemotherapy (1996) 40(4):920-923. Analysis of Phosphorylation Pathways of Antiherpesvirus Nucleosides by Varicella-Zoster Virus-Specific Enzymes
T. Suzutani
,
I. Yoshida
,
M. Azuma
2008
Corpus ID: 41511738
2000
2000
The role of cellular- and prodrug-associated factors in the bystander effect induced by the Varicella zoster and Herpes simplex viral thymidine kinases in suicide gene therapy
C. Grignet-Debrus
,
Vincent Cool
,
N. Baudson
,
T. Velu
,
C. Calberg‐Bacq
Cancer Gene Therapy
2000
Corpus ID: 31851757
To investigate the factors influencing the bystander effect — a key element in the efficacy of suicide gene therapy against…
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Highly Cited
1994
Highly Cited
1994
Cold-pressed peanut oils may contain peanut allergen.
Donald R. Hoffman
,
Cecil Collins-Williams
Journal of Allergy and Clinical Immunology
1994
Corpus ID: 26345981
Review
1993
Review
1993
Treatment of varicella in the immunocompetent adult
M. Wallace
,
W. Bowler
,
E. Oldfield
Journal of Medical Virology
1993
Corpus ID: 36507048
Varicella in the immunocompetent adult is an infrequent but potentially serious infection. Previous studies in immunocompetent…
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1991
1991
Clinical effect of BV-araU on varicella-zoster virus infection in immunocompromised patients with haematological malignancies.
A. Hiraoka
,
T. Masaoka
,
+5 authors
M. Takahashi
Journal of Antimicrobial Chemotherapy
1991
Corpus ID: 39856267
We evaluated the treatment of varicella-zoster infection with BV-araU in immuno-compromised patients with haematological…
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1990
1990
Drug Susceptibilities of Isolates of Varicella‐Zoster Virus in a Clinical Study of Oral Brovavir
H. Machida
,
M. Nishitani
Microbiology and immunology
1990
Corpus ID: 28307718
Susceptibilities to brovavir [l‐β‐D‐arabinofuranosyl‐E‐5‐(2‐bromovinyl)‐uracil] and acyclovir of clinical isolates of varicella…
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1984
1984
Investigation of antiviral activity of 1-beta-D-arabinofuranosylthymine (ara-T) and 1-beta-D-arabinofuranosyl-E-5-(2-bromovinyl)uracil (BV-ara-U) in monkeys infected with simian varicella virus.
K. Soike
,
G. Baskin
,
C. Cantrell
,
P. Gerone
Antiviral Research
1984
Corpus ID: 22209460
1984
1984
Strains of varicella-zoster virus resistant to 1-beta-D-arabinofuranosyl-E-5-(2-bromovinyl)uracil
T. Sakuma
Antimicrobial Agents and Chemotherapy
1984
Corpus ID: 11858648
Strains of varicella-zoster virus resistant to 1-beta-D-arabinofuranosyl-E-5-(2-bromovinyl)uracil (BV-araU) were isolated from…
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1979
1979
In Vitro Antiherpesviral Activity of 5-Alkyl Derivatives of 1-β-d-Arabinofuranosyluracil
H. Machida
,
S. Sakata
,
A. Kuninaka
,
H. Yoshino
,
C. Nakayama
,
M. Saneyoshi
Antimicrobial Agents and Chemotherapy
1979
Corpus ID: 39577864
Several 5-alkyl derivatives of 1-β-d-arabinofuranosyluracil (araU) were tested for antiherpesviral activity and inhibitory action…
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