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sodium phenylacetate

Known as: phenylacetic acid, sodium salt 
The sodium salt form of phenylacetate with ammonia detoxifying activity. Upon administration, sodium phenylacetate binds to glutamine thereby forming… 
National Institutes of Health

Related topics

Related topics

4 relations
50 ML Sodium Benzoate 100 MG/ML / sodium phenylacetate 100 MG/ML Injection

Narrower (1)

Ammonul

Broader (2)

phenylacetatephenylacetic acid

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
Matrix metalloproteinases are involved in both type I (apoptosis) and type II (autophagy) cell death induced by sodium phenylacetate in MDA-MB-231 breast tumour cells.
The effects of sodium phenylacetate (NaPa), an antitumoral molecule, on cell death and matrix metalloproteinase (MMP) activities… 
Review
2006
Review
2006
Pharmacology Review: Sodium Phenylacetate and Sodium Benzoate in the Treatment of Neonatal Hyperammonemia
Ammonia is present in all body fluids and exists primarily as ammonium ion at physiologic pH. Hyperammonemia is defined as a… 
2003
2003
Acute Postpartum Mental Status Change and Coma Caused by Previously Undiagnosed Ornithine Transcarbamylase Deficiency
2002
2002
A new phenylacetate-bisphosphonate inhibits breast cancer cell growth by proapoptotic and antiangiogenic effects.
Sodium phenylacetate (NaPa) and some bisphosphonates demonstrated antiproliferative and proapoptotic properties against cancer… 
2001
2001
Sodium phenylacetate enhances the inhibitory effect of dextran derivative on breast cancer cell growth in vitro and in nude mice
Sodium phenylacetate (NaPa) and carboxymethyl benzylamide dextran derivative (CMDBLS4) are able to inhibit growth of breast… 
1999
1999
Sodium phenylacetate (NaPa) induces modifications of the proliferation, the adhesion and the cell cycle of tumoral epithelial breast cells.
Sodium phenylacetate (NaPa), a physiological product of phenylalanine metabolism, present in micromolar concentrations in human… 
1998
1998
Sodium phenylacetate modulates the synthesis of autocrine and paracrine growth factors secreted by breast cancer cell lines.
Sodium Phenylacetate (NaPq) has been shown to suppress tumor growth and promote differentiation in experimental models. Thus, we… 
Highly Cited
1994
Highly Cited
1994
Growth inhibition, tumor maturation, and extended survival in experimental brain tumors in rats treated with phenylacetate.
Phenylacetate is a naturally occurring plasma component that suppresses the growth of tumor cells and induces differentiation in… 
1991
1991
Hyperargininemia: intellectual and motor improvement related to changes in biochemical data.
1981
1981
Evidence of lack of toxicity of sodium phenylacetate and sodium benzoate in treating urea cycle enzymopathies
EVIDENCE OF LACK OF TOXICITY OF SODIUM PHENYLACETATE AND SODIUM BENZOATE IN TREATING UREA CYCLE ENZYMOPATHIES A question… 
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