sodium phenylacetate

Known as: phenylacetic acid, sodium salt 
The sodium salt form of phenylacetate with ammonia detoxifying activity. Upon administration, sodium phenylacetate binds to glutamine thereby forming… Expand
National Institutes of Health

Papers overview

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Highly Cited
2007
Highly Cited
2007
BACKGROUND The combination of intravenous sodium phenylacetate and sodium benzoate has been shown to lower plasma ammonium levels… Expand
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Review
2004
Review
2004
Pools of farnesyl diphosphate and other phosphorylated products of the mevalonate pathway are essential to the post-translational… Expand
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2003
2003
Experimental allergic encephalomyelitis (EAE) is the animal model for multiple sclerosis. The present study underlines the… Expand
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Highly Cited
2001
Highly Cited
2001
The antifungal substances SH-1 and SH-2 were isolated from Streptomyces humidus strain S5-55 cultures by various purification… Expand
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Highly Cited
1997
Highly Cited
1997
This study explores the role of mevalonate inhibitors in the activation of NF-kbeta and the induction of inducible nitric oxide… Expand
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Highly Cited
1996
Highly Cited
1996
Malignant gliomas, the most common form of primary brain tumors, are highly dependent on the mevalonate (MVA) pathway for the… Expand
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1995
1995
BACKGROUND The growth-inhibiting and differentiating effects of sodium phenylacetate against hematopoietic and solid tumor cell… Expand
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Highly Cited
1993
Highly Cited
1993
Differentiation therapy may provide an alternative for treatment of cancers that do not respond to cytotoxic chemotherapy or… Expand
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Highly Cited
1992
Highly Cited
1992
Sodium phenylacetate was found to affect the growth and differentiation of tumor cells in vitro at concentrations that have been… Expand
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Highly Cited
1984
Highly Cited
1984
Although normal plasma ammonium levels can be maintained in children with inborn errors of ureagenesis, these children are… Expand
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