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slow axonal transport

The directed slow movement of non-membranous molecules in nerve cell axons. It is comprised of a slow component a" (SCa) and a "slow component b… Expand
National Institutes of Health

Related topics

Related topics

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Broader (1)

neuronal transport

Papers overview

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Review
2004
Review
2004
Slow axonal transport and the genesis of neuronal morphology.
The classic view of slow axonal transport maintains that microtubules, neurofilaments, and actin filaments move down the axon… Expand
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Review
2001
Review
2001
From charcot to lou gehrig: deciphering selective motor neuron death in als
Since its description by Charcot more than 130 years ago, the mechanism underlying the characteristic selective degeneration and… Expand
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Highly Cited
2000
Highly Cited
2000
Rapid movement of axonal neurofilaments interrupted by prolonged pauses
Axonal cytoskeletal and cytosolic proteins are synthesized in the neuronal cell body and transported along axons by slow axonal… Expand
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Highly Cited
2000
Highly Cited
2000
Neurofilaments Are Transported Rapidly But Intermittently in Axons: Implications for Slow Axonal Transport
Slow axonal transport conveys cytoskeletal proteins from cell body to axon tip. This transport provides the axon with the… Expand
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Highly Cited
2000
Highly Cited
2000
Glutamate Slows Axonal Transport of Neurofilaments in Transfected Neurons
Neurofilaments are transported through axons by slow axonal transport. Abnormal accumulations of neurofilaments are seen in… Expand
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Review
2000
Review
2000
Slow axonal transport: stop and go traffic in the axon
  • A. Brown
  • Nature Reviews Molecular Cell Biology
  • 2000
    • Corpus ID: 205010517
Efforts to observe the slow axonal transport of cytoskeletal polymers during the past decade have yielded conflicting results… Expand
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Highly Cited
1992
Highly Cited
1992
Local modulation of neurofilament phosphorylation, axonal caliber, and slow axonal transport by myelinating Schwann cells
Studies in Trembler and control mice demonstrated that myelinating Schwann cells exert a profound influence on axons. Extensive… Expand
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Highly Cited
1980
Highly Cited
1980
Axonal transport of the cytoskeleton in regenerating motor neurons: constancy and change
We have examined slow axonal transport in regenerating motor neurons of the rat sciatic nerve. Using SDS-PAGE (sodium dodecyl… Expand
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Highly Cited
1978
Highly Cited
1978
Slow axonal transport of neurofilament proteins: impairment of beta,beta'-iminodipropionitrile administration.
beta,beta'-Iminodipropionitrile (IDPN) administration prevented normal slow axonal transport of [35S]methionine- or [3H]leucine… Expand
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1971
1971
Role of slow axonal transport in nerve regeneration.
After section of the optic tract in goldfish, axonal outgrowth begins 6–8 days after the cut and is accompanied by an increase in… Expand
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