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siomycin A

Known as: 1-valine-2-(2,3-didehydroalanine)thiostrepton 
National Institutes of Health

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Peptides

Papers overview

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2019
2019
Effects and mechanism of siomycin A on the growth and apoptosis of MiaPaCa-2 cancer cells
Siomycin A is a type of thiopeptide antibiotic that is isolated from the fermentation products of an endophytic actinomycin… 
2013
2013
Targeting FOXM1 Transcription Factor In T-Cell Acute Lymphoblastic Leukemia
The Forkhead box protein M1(FoxM1) is an important  transcriptional factor that takes play in regulation of cell cyle… 
2010
2010
New potential anti‐cancer agents synergize with bortezomib and ABT‐737 against prostate cancer
We previously described the identification of a transcriptional inhibitor ARC and FoxM1 inhibitors, thiazole antibiotics… 
1969
1969
Studies on siomycin. V. Derivatives of siomycin A prepared with thiolcarboxylic acid.
shows relatively low toxicity. However, the greatest problem with this antibiotic is its insolubility in water2). In the course… 
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