siomycin A

Known as: 1-valine-2-(2,3-didehydroalanine)thiostrepton 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1969-2017
02419692017

Papers overview

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Highly Cited
2013
Highly Cited
2013
Glioblastoma multiforme (GBM) is a life-threatening brain tumor. Accumulating evidence suggests that eradication of glioma stem… (More)
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2013
2013
of FOXM1 (Gartel, 2010, 2012). According to this model, siomycin A, thiostrepton, and other proteasome inhibitors hinder the… (More)
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2011
2011
Glioblastoma multiforme (GBM) is a devastating disease, and the current therapies have only palliative effect. Evidence is… (More)
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2011
2011
PURPOSE The transcription factor Forkhead box M1 (FoxM1) is a key regulator of cell-cycle progression. It is involved in the… (More)
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Highly Cited
2009
Highly Cited
2009
Forkhead box M1 (FoxM1) oncogenic transcription factor represents an attractive therapeutic target in the fight against cancer… (More)
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Highly Cited
2009
Highly Cited
2009
Proteasome inhibitors are currently in the clinic or in clinical trials, but the mechanism of their anticancer activity is not… (More)
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2008
2008
The five practical segments for the total synthesis of siomycin A, that is, the dehydropiperidine segment A (5), the pentapeptide… (More)
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2008
2008
We previously described the identification of a nucleoside analog transcriptional inhibitor ARC (4-amino-6-hydrazino-7-beta-D… (More)
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2008
2008
The total synthesis of siomycin A (1), a representative compound of the thiostrepton family of peptide antibiotics, was achieved… (More)
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Highly Cited
2006
Highly Cited
2006
The oncogenic transcription factor forkhead box M1 (FoxM1) is overexpressed in a number of different carcinomas, whereas its… (More)
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