silvestrol
National Institutes of Health
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FGFR1-activated Translation of WNT Pathway Components with Structured 1 5' UTRs is Vulnerable to Inhibition of EIF4A-dependent…
It is well accepted that post-transcriptional control makes a significant contribution to the overall regulation of gene…
Hypoxic non‐small cell lung cancer (NSCLC) is dependent on Notch‐1 signaling for survival. Targeting Notch‐1 by means of…
During B-lymphocyte development, antigen engagement of the B-cell receptor (BCR) propagates signals promoting cell growth…
Ribosome activity is linked to the activity of a transcription factor in cancer cells. [Also see Research Article by Santagata et…
Abstract 3498 During cell cycle progression, D class cyclins activate cyclin dependent kinases (CDK) 4 and 6 to phosphorylate and…
The article discusses the total synthesis of the rare and potent anticancer plant natural products silvestrol and its…
Chronic Lymphocytic Leukemia (CLL) is an incurable disease with limited therapeutic options, especially for high-risk populations…
Chronic Lymphocytic Leukemia (CLL) is an incurable disease with limited therapeutic options. The development of drug resistance…