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silodosin

Known as: 1-(3-hydroxypropyl)-5-(2-(2-(2-(2,2,2-trifluoroethoxy)phenoxy)ethylamino)propyl)indoline-7-carboxamide 
An orally available, alpha-1 adrenoreceptor (alpha-1a) selective antagonist that can be used to relieve symptoms of benign prostate hyperplasia (BPH… 
National Institutes of Health

Related topics

Related topics

7 relations

Broader (3)

Adrenergic alpha-1 Receptor AntagonistsIndolesUrological Agents
Adrenergic alpha-Antagonists [MoA]silodosin 4 MG Oral Capsule [Rapaflo]

Narrower (2)

KAD 3213KMD 3213

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
α1A-Adrenergic Receptor Antagonism Improves Erectile and Cavernosal Responses in Rats With Cavernous Nerve Injury and Enhances Neurogenic Responses in Human Corpus Cavernosum From Patients With…
2015
2015
Intraoperative floppy iris syndrome associated with silodosin
Editor, W e read the article by StorrPaulsen et al. (2014) with great interests. They contributed literature with a large numbers… 
2013
2013
Naftopidil inhibits 5-hydroxytryptamine-induced bladder contraction in rats.
2013
2013
Administration of the selective alpha 1A-adrenoceptor antagonist silodosin facilitates expulsion of size 5–10 mm distal ureteral stones, as compared to control
ObjectiveRecently, we reported that alpha 1A-adrenoceptor (AR) is the main participant in phenylephrine-induced human ureteral… 
Review
2013
Review
2013
[Sexual side effects of pharmacological treatments].
2013
2013
Characterization of silodosin and naftopidil in the treatment of bladder dysfunction in the spontaneously hypertensive rat
As increasing evidence suggest that α1‐blockers prevent benign prostatic hyperplasia related overactive bladder and nocturia in… 
2011
2011
Effect of silodosin on detrusor overactivity in the male spontaneously hypertensive rat
What's known on the subject? and What does the study add? 
2008
2008
In vivo study on the effects of alpha1-adrenoceptor antagonists on intraurethral pressure in the prostatic urethra and intraluminal pressure in the vas deferens in male dogs.
2008
2008
Different affinities of native alpha1B-adrenoceptors for ketanserin between intact tissue segments and membrane preparations.
2007
2007
Identification of α-1L and α-1A Adrenoceptors in Human Prostate by Tissue Segment Binding
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