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silodosin

Known as: 1-(3-hydroxypropyl)-5-(2-(2-(2-(2,2,2-trifluoroethoxy)phenoxy)ethylamino)propyl)indoline-7-carboxamide 
An orally available, alpha-1 adrenoreceptor (alpha-1a) selective antagonist that can be used to relieve symptoms of benign prostate hyperplasia (BPH… 
National Institutes of Health

Related topics

Related topics

7 relations

Broader (3)

Adrenergic alpha-1 Receptor AntagonistsIndolesUrological Agents
Adrenergic alpha-Antagonists [MoA]silodosin 4 MG Oral Capsule [Rapaflo]

Narrower (2)

KAD 3213KMD 3213

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Determination of silodosin and its active glucuronide metabolite KMD-3213G in human plasma by LC-MS/MS for a bioequivalence study.
A sensitive and selective liquid chromatography-tandem mass spectrometry (LC-MS/MS) method is described for the simultaneous… 
2016
2016
α1A-Adrenergic Receptor Antagonism Improves Erectile and Cavernosal Responses in Rats With Cavernous Nerve Injury and Enhances Neurogenic Responses in Human Corpus Cavernosum From Patients With…
Review
2016
Review
2016
[Lower urinary tract symptoms and pelvic floor dysfunction in renal transplant candidates and recipients].
2013
2013
Naftopidil inhibits 5-hydroxytryptamine-induced bladder contraction in rats.
Review
2013
Review
2013
[Sexual side effects of pharmacological treatments].
2013
2013
Alpha1A-adrenergic control of piloerection and palpebral fissure width in rats
2012
2012
Excitatory effect of propiverine hydrochloride on urethral activity in rats
Objectives:  To investigate the effects of the antimuscarinic agent, propiverine, on the bladder and urethra in rats. 
2008
2008
In vivo study on the effects of alpha1-adrenoceptor antagonists on intraurethral pressure in the prostatic urethra and intraluminal pressure in the vas deferens in male dogs.
2008
2008
Different affinities of native alpha1B-adrenoceptors for ketanserin between intact tissue segments and membrane preparations.
2007
2007
Identification of α-1L and α-1A Adrenoceptors in Human Prostate by Tissue Segment Binding
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