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sifuvirtide

National Institutes of Health

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Peptides

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
HIV-1 gp41-targeting fusion inhibitory peptides enhance the gp120-targeting protein-mediated inactivation of HIV-1 virions
Protein- or peptide-based viral inactivators are being developed as novel antiviral drugs with improved efficacy… 
2017
2017
A novel preventive strategy against HIV-1 infection: combinatorial use of inhibitors targeting the nucleocapsid and fusion proteins
The strategy of simultaneously attacking multiple targets is worthy of exploration in the field of microbicide development to… 
Review
2016
Review
2016
Evaluation of the Therapeutic Properties of Mastoparan- and Sifuvirtide- Derivative Antimicrobial Peptides Using Chemical Structure-Function Relationship - in vivo and in silico Approaches.
Antimicrobial peptides, also called body defense peptides, are chemical structures widely distributed across the animal and… 
2016
2016
Mucosal Topical Microbicide Candidates Exert Influence on the Subsequent SIV Infection and Survival by Regulating SIV-Specific T-Cell Immune Responses
Objective:To determine whether mucosal topical microbicides have any influence on disease progression during subsequent simian… 
2016
2016
Computer-Aided Druggability Detector: A Computerized Apparatus for Quickening Drug Discovery Processes
Druggability is the process of authenticating the level of fitness or complementariness of therapeutic interventions to their… 
2010
2010
Unravelling the molecular basis of the selectivity of the HIV-1 fusion inhibitor sifuvirtide towards phosphatidylcholine-rich rigid membranes.
2010
2010
The role of blood cell membrane lipids on the mode of action of HIV-1 fusion inhibitor sifuvirtide.
2010
2010
The rare HIV-1 gp41 mutations 43T and 50V elevate enfuvirtide resistance levels of common enfuvirtide resistance mutations that did not impact susceptibility to sifuvirtide.
2005
2005
Pharmacokinetics of sifuvirtide, a novel anti-HIV-1 peptide, in monkeys and its inhibitory concentration in vitro
AbstractAim:To study the pharmacokinetics of sifuvirtide, a novel anti-human immunodeficiency virus (HIV) peptide, in monkeys and… 
2005
2005
Quantification of sifuvirtide in monkey plasma by an on-line solid-phase extraction procedure combined with liquid chromatography/electrospray ionization tandem mass spectrometry.
A simple, automated and rapid method has been developed for the determination of a novel antiviral peptide sifuvirtide in monkey… 
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