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shepherdin

National Institutes of Health

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Peptide Fragments

Papers overview

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2015
2015
Influence of the survivin inhibitor shepherdin on proliferation, migration and apoptosis of Rhabdomyosarcoma tumor cells
2013
2013
Transducing properties of a pre-structured α-helical DPT-peptide containing a short canine adenovirus type 2 E4orf4 PP2A1-binding sequence.
2010
2010
Adeno-Associated Virus Harboring Fusion Gene NT4-Ant-Shepherdin Induce Cell Death in Human Lung Cancer Cells
ABSTRACT To further enhance anticancer effect of Shepherdin and overcome limitation of peptide therapy, recombinant adeno… 
2010
2010
Combined in Silico and Experimental Approach for Drug Design: The Binding Mode of Peptidic and Non‐Peptidic Inhibitors to Hsp90 N‐Terminal Domain
Heat shock protein 90 (Hsp90) is a prime target for antitumor therapies. The information obtained by molecular dynamics (MD… 
2009
2009
The augmentation of intracellular delivery of peptide therapeutics by artificial protein transduction domains.
2009
2009
TRAP1, a novel antiapoptotic gene responsible for multidrug resistance in human colorectal carcinoma cells.
2541 Background: TRAP1 has been recently described as a component of a mitochondrial pathway selectively up- regulated in tumor… 
2005
2005
Antileukemic Activity of Shepherdin, a Novel Targeted Inhibitor of the Survivin-Hsp90 Complex.
Cancer therapy now aims at disabling critical signaling pathways essential for tumor cell maintenance without affecting normal… 
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