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setipiprant

National Institutes of Health

Papers overview

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2017
2017
AbstractBackgroundAntagonism of chemoattractant receptor-homologous molecule on T-helper type-2 cells (CRTH2), a G-protein… Expand
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2015
2015
Abstract Biomarkers have shown to improve success rates in the development of novel drugs, providing essential information in the… Expand
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2015
2015
Background and ObjectiveThe chemoattractant receptor-homologous molecule expressed on T helper-2 cells (CRTH2) is a G-protein… Expand
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2015
2015
Various racemic and enantioenriched (trans)-X,Y-dihydroxy-X,Y-dihydronaphthoyl analogues as well as X-hydroxy-naphthoyl analogues… Expand
Highly Cited
2014
Highly Cited
2014
CRTH2 is a G‐protein‐coupled receptor on T helper2 cells that mediates pro‐inflammatory effects of prostaglandin D2 in allergic… Expand
2014
2014
Chemoattractant receptor‐homologous molecule expressed on T helper (Th) 2 cells (CRTH2) is a G‐protein‐coupled receptor for… Expand
2014
2014
PurposeSetipiprant, a selective oral CRTH2 antagonist, has been investigated for the treatment of allergic rhinitis and asthma… Expand
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2013
2013
Herein we describe the discovery of the novel CRTh2 antagonist 2-(2-(1-naphthoyl)-8-fluoro-3,4-dihydro-1H-pyrido[4,3-b]indol-5(2H… Expand
2013
2013
BackgroundSetipiprant, a tetrahydropyridoindole derivative, is a CRTH2 (chemoattractant receptor-homologous molecule expressed on… Expand
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2013
2013
BACKGROUND CRTH2 is a prostaglandin D2 receptor that plays an important role in allergic inflammation. Setipiprant is a potent… Expand