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sclareol

Known as: labd-14-ene-8alpha, 13beta-diol 
 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

Diterpenes

Narrower (1)

sclareol oxide

Papers overview

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Highly Cited
2012
Highly Cited
2012
Toward a biosynthetic route to sclareol and amber odorants.
Ambergris, a waxy substance excreted by the intestinal tract of the sperm whale, has been a highly prized fragrance ingredient… Expand
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Highly Cited
2012
Highly Cited
2012
Discovery and functional characterization of two diterpene synthases for sclareol biosynthesis in Salvia sclarea (L.) and their relevance for perfume manufacture
BackgroundSclareol is a diterpene natural product of high value for the fragrance industry. Its labdane carbon skeleton and its… Expand
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2012
2012
Sclareol exhibits anti-inflammatory activity in both lipopolysaccharide-stimulated macrophages and the λ-carrageenan-induced paw edema model.
Sclareol (1) is a natural fragrance compound used widely in the cosmetic and food industries. Lipopolysaccharide (LPS)-stimulated… Expand
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2010
2010
Mitochondria-targeted liposomes improve the apoptotic and cytotoxic action of sclareol
Current efforts toward improving the effectiveness of drug therapy are increasingly relying on drug-targeting strategies to… Expand
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2006
2006
Cytotoxic and antitumor activity of liposome-incorporated sclareol against cancer cell lines and human colon cancer xenografts.
The aim of this study was to design and prepare liposome-incorporated sclareol--a highly lipophilic natural product-to overcome… Expand
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2006
2006
Labd-14-ene-8,13-diol (sclareol) induces cell cycle arrest and apoptosis in human breast cancer cells and enhances the activity of anticancer drugs.
Sclareol is a labdane-type diterpene that has demonstrated a significant cytotoxic activity against human leukemic cell lines… Expand
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Highly Cited
2005
Highly Cited
2005
NpPDR1, a Pleiotropic Drug Resistance-Type ATP-Binding Cassette Transporter from Nicotiana plumbaginifolia, Plays a Major Role in Plant Pathogen Defense1
Nicotiana plumbaginifolia NpPDR1, a plasma membrane pleiotropic drug resistance-type ATP-binding cassette transporter formerly… Expand
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2004
2004
Biosynthesis of labdenediol and sclareol in cell-free extracts from trichomes of Nicotiana glutinosa
Biosynthesis of the diterpenes labdenediol and sclareol from all trans-geranylgeranyl pyrophosphate was observed in cell-free… Expand
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Highly Cited
2003
Highly Cited
2003
Pathogen-Responsive Expression of a Putative ATP-Binding Cassette Transporter Gene Conferring Resistance to the Diterpenoid Sclareol Is Regulated by Multiple Defense Signaling Pathways in…
The ATP-binding cassette (ABC) transporters are encoded by large gene families in plants. Although these proteins are potentially… Expand
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Highly Cited
2002
Highly Cited
2002
The ABC transporter SpTUR2 confers resistance to the antifungal diterpene sclareol.
PDR5-like proteins represent one group of the ABC superfamily of transporters. Members of this group are present in plants and… Expand
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