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ryanodol

National Institutes of Health

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Ryanodine
analogs & derivatives

Papers overview

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2019
2019
Studies Targeting Ryanodol Result in an Annulation Reaction for the Synthesis of a Variety of Fused Carbocycles.
An annulation reaction is described to access a range of polycyclic and highly oxygenated carbocycles. First developed in an… 
2017
2017
Construction of Quaternary Stereogenic Centers in the Total Synthesis of Natural Products.
  • E. Prusov
  • Angewandte Chemie
  • 2017
  • Corpus ID: 45140562
Total syntheses of the tetracyclic terpene waihoensene and the densely functionalized tetracyclic compound ryanodol have recently… 
2016
2016
Unified Total Synthesis of 3-epi-Ryanodol, Cinnzeylanol, Cinncassiols A and B, and Structural Revision of Natural Ryanodol and Cinnacasol.
Ryanodane diterpenoids structurally share an extremely complex fused ring system, but differ in the substitution patterns of the… 
2016
2016
Chemical Conversion of Ryanodol to Ryanodine.
Ryanodine (1) is a plant-derived natural product with powerful pharmacological and insecticidal action, and is a potent modulator… 
2008
2008
Ryanoids and imperatoxin affect the modulation of cardiac ryanodine receptors by dihydropyridine receptor Peptide A.
2004
2004
Effects of ryanoids on spontaneous and depolarization-evoked calcium release events in frog muscle.
The effects of ryanoids on calcium sparks and transients were studied in voltage-clamped cut frog muscle fibers with a laser… 
2003
2003
Residue Gln4863 within a Predicted Transmembrane Sequence of the Ca2+ Release Channel (Ryanodine Receptor) Is Critical for Ryanodine Interaction*
Despite the pivotal role of ryanodine in ryanodine receptor (RyR) research, the molecular basis of ryanodine-RyR interaction… 
2001
2001
Ryanoid Modification of the Cardiac Muscle Ryanodine Receptor Channel Results in Relocation of the Tetraethylammonium Binding Site
The interaction of ryanodine and derivatives of ryanodine with the high affinity binding site on the ryanodine receptor (RyR… 
2000
2000
The Interaction of a Neutral Ryanoid with the Ryanodine Receptor Channel Provides Insights into the Mechanisms by Which Ryanoid Binding Is Modulated by Voltage
In an earlier investigation, we demonstrated that the likelihood of interaction of a positively charged ryanoid, 21-amino-9… 
1996
1996
The pyrrole locus is the major orienting factor in ryanodine binding.
Ryanodine, a natural product, is a complex modulator of a class of intracellular Ca2+ release channels commonly called the… 
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