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rotundifolone

National Institutes of Health

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Monoterpenes

Papers overview

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2016
2016
Evaluation of Antiparasitc Activity of Mentha crispa Essential Oil, Its Major Constituent Rotundifolone and Analogues against Trypanosoma brucei
Abstract Considering the pressing need for new drugs to treat sleeping sickness and Nagana disease, Mentha crispa essential oil… 
2015
2015
TRPM8 Channel Activation Induced by Monoterpenoid Rotundifolone Underlies Mesenteric Artery Relaxation
In this study, our aims were to investigate transient receptor potential melastatin-8 channels (TRPM8) involvement in… 
2014
2014
A New Source of (R)-Limonene and Rotundifolone from Leaves of Lippia pedunculosa (Verbenaceae) and their Trypanocidal Properties
Investigation by GC-FID and GC-MS of the essential oil (LPOE) from the leaves of Lippia pedunculosa revealed, as the major… 
Review
2011
Review
2011
Cardiovascular effects of monoterpenes: a review
The monoterpenes are secondary metabolites of plants. They have various pharmacological properties including antifungal… 
2011
2011
Rotundifolone-induced relaxation is mediated by BK(Ca) channel activation and Ca(v) channel inactivation.
Rotundifolone is the major constituent of the essential oil of Mentha x villosa Hudson. In preliminary studies, rotundifolone… 
2008
2008
Structure and Spasmolytic Activity Relationships of Monoterpene Analogues Found in Many Aromatic Plants
Abstract Rotundifolone, a monoterpene isolated from the essential oil of the leaves of Mentha x villosa, is a constituent of… 
Highly Cited
2007
Highly Cited
2007
Antinociceptive Activity of Structural Analogues of Rotundifolone: Structure-Activity Relationship
Rotundifolone, a monoterpene isolated from the essential oil of the leaves of Mentha x villosa, is a constituent of several… 
2004
2004
Calcium antagonism and the vasorelaxation of the rat aorta induced by rotundifolone.
The vasorelaxing activity of rotundifolone (ROT), a major constituent (63.5%) of the essential oil of Mentha x villosa, was… 
2002
2002
Muscarinic Agonist Properties Involved in the Hypotensive and Vasorelaxant Responses of Rotundifolone in Rats
Mentha x villosa in vivo in vitro i. v. i. v. L i. v. L 
1996
1996
Analgesic effect of rotundifolone in rodents
Rotundifolone (1), an oxygenated monoterpene isolated from the essential oil of the leaves of M. x villosa, showed significant… 
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