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rostafuroxin
Known as:
17-(3-furyl)-5beta-androstane-3,14,17-triol
National Institutes of Health
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Related topics
Related topics
2 relations
Broader (1)
Androstanols
Narrower (1)
PST 2238
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Ouabain–digoxin antagonism in rat arteries and neurones
Hong Song
,
E. Karashima
,
J. Hamlyn
,
M. Blaustein
The Journal of physiology
2014
Corpus ID: 19498410
‘Classic’ cardiotonic steroids (CTSs) all inhibit Na+,K+‐ATPase (Na+ pumps) and exert cardiotonic and vasotonic effects…
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Review
2012
Review
2012
Systemic Hypertension: The Roles of Salt, Vascular Na+/K+ ATPase and the Endogenous Glycosides, Ouabain and Marinobufagenin
C. Hauck
,
W. Frishman
Cardiology in review
2012
Corpus ID: 205567227
Essential hypertension has been shown to be significantly associated with an increased risk for cardiovascular disease and is not…
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Highly Cited
2011
Highly Cited
2011
Mania-like behavior induced by genetic dysfunction of the neuron-specific Na+,K+-ATPase α3 sodium pump
G. Kirshenbaum
,
S. Clapcote
,
+10 authors
J. Roder
Proceedings of the National Academy of Sciences
2011
Corpus ID: 10147227
Bipolar disorder is a debilitating psychopathology with unknown etiology. Accumulating evidence suggests the possible involvement…
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2011
2011
Main results of the Ouabain and Adducin for Specific Intervention on Sodium in Hypertension Trial (OASIS-HT): a randomized placebo-controlled phase-2 dose-finding study of rostafuroxin
J. Staessen
,
L. Thijs
,
+19 authors
G. Bianchi
Trials
2011
Corpus ID: 14561537
BackgroundThe Ouabain and Adducin for Specific Intervention on Sodium in Hypertension (OASIS-HT) Trial was a phase-2 dose-finding…
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Highly Cited
2010
Highly Cited
2010
Adducin- and Ouabain-Related Gene Variants Predict the Antihypertensive Activity of Rostafuroxin, Part 2: Clinical Studies
C. Lanzani
,
L. Citterio
,
+13 authors
G. Bianchi
Science Translational Medicine
2010
Corpus ID: 12719921
Five genetic variants that affect Na,K-ATPase interactions predict the blood pressure response to rostafuroxin but not to…
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2010
2010
Adducin- and Ouabain-Related Gene Variants Predict the Antihypertensive Activity of Rostafuroxin, Part 1: Experimental Studies
M. Ferrandi
,
I. Molinari
,
+5 authors
G. Bianchi
Science Translational Medicine
2010
Corpus ID: 206677382
Rostafuroxin lowers blood pressure in rats and disrupts mutant α-adducin and ouabain–Na,K-ATPase complex interaction with the Src…
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Review
2010
Review
2010
Genetics of primary hypertension: the clinical impact of adducin polymorphisms.
L. Citterio
,
C. Lanzani
,
P. Manunta
,
G. Bianchi
Biochimica et biophysica acta
2010
Corpus ID: 563174
2007
2007
Targeting Ouabain- and Adducin-dependent mechanisms of hypertension and cardiovascular remodeling as a novel pharmacological approach.
P. Ferrari
,
M. Ferrandi
,
G. Valentini
,
P. Manunta
,
G. Bianchi
Medical hypotheses
2007
Corpus ID: 33820659
Review
2007
Review
2007
Endogenous and Exogenous Cardiac Glycosides and their Mechanisms of Action
W. Schoner
,
G. Scheiner-Bobis
American journal of cardiovascular drugs : drugs…
2007
Corpus ID: 31575648
Cardiac glycosides have been used for decades to treat congestive heart failure. The recent identification of cardiotonic…
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Review
2006
Review
2006
Rostafuroxin: an ouabain antagonist that corrects renal and vascular Na+-K+- ATPase alterations in ouabain and adducin-dependent hypertension.
P. Ferrari
,
M. Ferrandi
,
G. Valentini
,
G. Bianchi
American journal of physiology. Regulatory…
2006
Corpus ID: 25816680
The genetic and environmental heterogeneity of essential hypertension is responsible for the individual variability of…
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