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rostafuroxin

Known as: 17-(3-furyl)-5beta-androstane-3,14,17-triol 
 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
‘Classic’ cardiotonic steroids (CTSs) all inhibit Na+,K+‐ATPase (Na+ pumps) and exert cardiotonic and vasotonic effects… Expand
Review
2012
Review
2012
Essential hypertension has been shown to be significantly associated with an increased risk for cardiovascular disease and is not… Expand
Highly Cited
2011
Highly Cited
2011
Bipolar disorder is a debilitating psychopathology with unknown etiology. Accumulating evidence suggests the possible involvement… Expand
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2011
2011
BackgroundThe Ouabain and Adducin for Specific Intervention on Sodium in Hypertension (OASIS-HT) Trial was a phase-2 dose-finding… Expand
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Highly Cited
2010
Highly Cited
2010
Five genetic variants that affect Na,K-ATPase interactions predict the blood pressure response to rostafuroxin but not to… Expand
Review
2010
Review
2010
  • P. Ferrari
  • Biochimica et biophysica acta
  • 2010
  • Corpus ID: 19192222
An innovative approach to the therapy of essential hypertension (EH) and the related complications has been pursued by our group… Expand
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2010
2010
Rostafuroxin lowers blood pressure in rats and disrupts mutant α-adducin and ouabain–Na,K-ATPase complex interaction with the Src… Expand
2009
2009
Background Endogenous ouabain, an endogenous digitalis-like steroid, is synthesized in the adrenal glands and possibly in the… Expand
Review
2007
Review
2007
Cardiac glycosides have been used for decades to treat congestive heart failure. The recent identification of cardiotonic… Expand
Review
2006
Review
2006
The genetic and environmental heterogeneity of essential hypertension is responsible for the individual variability of… Expand
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