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ribose-phosphate pyrophosphokinase activity

Known as: ribose phosphate diphosphokinase activity, 5-phosphoribosyl-alpha-1-pyrophosphate synthetase activity, phosphoribosyl pyrophosphate synthetase activity 
Catalysis of the reaction: D-ribose 5-phosphate + ATP = 5-phospho-alpha-D-ribose 1-diphosphate + AMP + 2 H(+). [EC:2.7.6.1, RHEA:15612]
National Institutes of Health

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1995
1995
The gcaD, prs, and ctc genes were shown to be organized as a tricistronic operon. The transcription of the prs gene, measured as… 
Highly Cited
1989
Highly Cited
1989
A DNA fragment encoding kanamycin resistance was inserted in vitro into a plasmid‐borne prs gene encoding… 
1981
1981
Two male patients with urate overexcretion and clinical gout in a family showed activity of phosphoribosylpyrophosphate (PRPP… 
1976
1976
In subconfluent cultures of fibroblasts from patients with complete or partial deficiencies of hypoxanthine-guanine… 
1975
1975
The activity of phosphoribosylpyrophosphate synthetase and the rate of phosphoribosylpyrophosphate accumulation are significantly… 
Highly Cited
1973
Highly Cited
1973
In hemolyzates from red cells of two brothers with purine overproduction and gout, activity of phosphoribosylpyrophosphate… 
Highly Cited
1973
Highly Cited
1973
Highly Cited
1973
Among affected members of a family (B. family) with excessive purine production and gout, activity of phosphoribosylpyrophosphate…