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ribose-phosphate pyrophosphokinase activity

Known as: ribose phosphate diphosphokinase activity, 5-phosphoribosyl-alpha-1-pyrophosphate synthetase activity, phosphoribosyl pyrophosphate synthetase activity 
Catalysis of the reaction: D-ribose 5-phosphate + ATP = 5-phospho-alpha-D-ribose 1-diphosphate + AMP + 2 H(+). [EC:2.7.6.1, RHEA:15612]
National Institutes of Health

Papers overview

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1992
1992
A new Escherichia coli mutant named dnaR, which was temperature sensitive in initiation of DNA replication, has been… Expand
Highly Cited
1989
Highly Cited
1989
A DNA fragment encoding kanamycin resistance was inserted in vitro into a plasmid‐borne prs gene encoding… Expand
1982
1982
An assay procedure, utilizing high pressure liquid chromatography, has been designed which allows both reactions catalyzed by… Expand
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1981
1981
Two male patients with urate overexcretion and clinical gout in a family showed activity of phosphoribosylpyrophosphate (PRPP… Expand
1976
1976
In subconfluent cultures of fibroblasts from patients with complete or partial deficiencies of hypoxanthine-guanine… Expand
1975
1975
The activity of phosphoribosylpyrophosphate synthetase and the rate of phosphoribosylpyrophosphate accumulation are significantly… Expand
Highly Cited
1973
Highly Cited
1973
In hemolyzates from red cells of two brothers with purine overproduction and gout, activity of phosphoribosylpyrophosphate… Expand
Highly Cited
1973
Highly Cited
1973
Abstract Two brothers with marked purine overproduction and clinical gout showed activity of the enzyme… Expand
Highly Cited
1973
Highly Cited
1973
Among affected members of a family (B. family) with excessive purine production and gout, activity of phosphoribosylpyrophosphate… Expand
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