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ribonucleotide excision repair

The pathway by which a ribonucleotide is removed from DNA and replaced by a deoxyribonucleotide. The ribonucleotide is incised by RNase H2, and… 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Unlike the Escherichia coli counterpart, archaeal RNase HII cannot process ribose monophosphate abasic sites and oxidized ribonucleotides embedded in DNA
The presence of ribonucleoside monophosphates (rNMPs) in nuclear DNA decreases genome stability. To ensure survival despite rNMP… 
2018
2018
Mapping Ribonucleotides Incorporated into DNA by Hydrolytic End-Sequencing.
Ribonucleotides embedded within DNA render the DNA sensitive to the formation of single-stranded breaks under alkali conditions… 
2018
2018
Genomic Ribonucleotides Produce PARP-Trapping Lesions.
Mutations in RNASEH2B impair ribonucleotide excision repair to confer PARP inhibitor sensitivity. 
2017
2017
Defining the RNaseH2 enzyme-initiated ribonucleotide excision repair pathway in Archaea
Incorporation of ribonucleotides during DNA replication has severe consequences for genome stability. Although eukaryotes possess… 
Highly Cited
2017
Highly Cited
2017
Nucleotide pools dictate the identity and frequency of ribonucleotide incorporation in mitochondrial DNA
Previous work has demonstrated the presence of ribonucleotides in human mitochondrial DNA (mtDNA) and in the present study we use… 
2017
2017
Both R-loop removal and ribonucleotide excision repair activities of RNase H2 contribute substantially to chromosome stability.
2017
2017
Bases genéticas y moleculares del Síndrome de Aicardi-Goutières (AGS)
Objetive: The purpose of this work was to demonstrate the connection between the mutations in any of  the RNaseH2 complex’s… 
2016
2016
Increased spontaneous recombination in RNase H2-deficient cells arises from multiple contiguous rNMPs and not from single rNMP residues incorporated by DNA polymerase epsilon
Ribonucleotides can become embedded in DNA from insertion by DNA polymerases, failure to remove Okazaki fragment primers, R-loops… 
Review
2016
Review
2016
Eukaryotic genome instability in light of asymmetric DNA replication
Abstract The eukaryotic nuclear genome is replicated asymmetrically, with the leading strand replicated continuously and the… 
2012
2012
Molecular Cell RNase H 2-Initiated Ribonucleotide Excision Repair
Justin L. Sparks,1 Hyongi Chon,2 Susana M. Cerritelli,2 Thomas A. Kunkel,3 Erik Johansson,4 Robert J. Crouch,2 and Peter M… 
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