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ribavirin amidine

Known as: TARIBAVIRIN, 1-beta-D-ribofuranosyl-1,2,4-triazole-3-carboxamidine, viramidine 
An orally available prodrug of ribavirin, a synthetic nucleoside analog of ribofuranose with activity against a wide range of viruses, especially the… Expand
National Institutes of Health

Related topics

Related topics

3 relations

Broader (1)

Ribavirin
Taribavirin Hydrochlorideanalogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2007
Review
2007
Strategies for Managing Anemia in Hepatitis C Patients Undergoing Antiviral Therapy
Anemia is a common side effect that begins soon after the initiation of peginterferon/ribavirin in the treatment of hepatitis C… Expand
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Review
2007
Review
2007
The kidney transplant recipient with hepatitis C infection: pre- and posttransplantation treatment.
Liver disease secondary to chronic hepatitis C virus (HCV) infection is an important cause of morbidity and mortality in dialysis… Expand
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2007
2007
Comparison of the inhibitory effects of interferon alfacon-1 and ribavirin on yellow fever virus infection in a hamster model.
Antiviral compounds were evaluated for efficacy against yellow fever virus (YFV) in a hamster model of YFV-induced liver disease… Expand
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2007
2007
Virological response and safety outcomes in therapy-nai ve patients treated for chronic hepatitis C with taribavirin or ribavirin in combination with pegylated interferon alfa-2a: a randomized, phase…
BACKGROUND/AIMS Pegylated interferon plus ribavirin can cause dose-limiting anemia. Taribavirin, a ribavirin prodrug, has shown a… Expand
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Review
2006
Review
2006
Definition and management of anemia in patients infected with hepatitis C virus.
Chronic infection with hepatitis C virus (HCV) can progress to cirrhosis, hepatocellular carcinoma, and end-stage liver disease… Expand
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Review
2006
Review
2006
Treating HCV with ribavirin analogues and ribavirin-like molecules.
  • Robert Gish
  • The Journal of antimicrobial chemotherapy
  • 2006
    • Corpus ID: 17475452
Nucleos(t)ide analogues have proven useful in the treatment of viral infections. Ribavirin is a nucleoside, guanosine analogue… Expand
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2005
2005
Phosphorylation of ribavirin and viramidine by adenosine kinase and cytosolic 5'-nucleotidase II: Implications for ribavirin metabolism in erythrocytes.
Many nucleoside analog drugs, such as ribavirin and viramidine, are activated or metabolized in vivo through 5'-phosphorylation… Expand
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2004
2004
A simple assay for determining antiviral activity against Crimean-Congo hemorrhagic fever virus.
Crimean-Congo hemorrhagic fever virus (CCHFV) is a tick-borne virus that is emerging as a significant human pathogen in many… Expand
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2003
2003
Activation and deactivation of a broad-spectrum antiviral drug by a single enzyme: adenosine deaminase catalyzes two consecutive deamination reactions.
Ribavirin is an approved broad-spectrum antiviral drug. A liver-targeting prodrug of ribavirin, viramidine, is in clinical trial… Expand
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2003
2003
Viramidine, a Prodrug of Ribavirin, Shows Better Liver-Targeting Properties and Safety Profiles Than Ribavirin in Animals
Ribavirin, part of the current first line combination therapy for the treatment of chronic hepatitis C, may cause haemolytic… Expand
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