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ribavirin amidine

Known as: TARIBAVIRIN, 1-beta-D-ribofuranosyl-1,2,4-triazole-3-carboxamidine, viramidine 
An orally available prodrug of ribavirin, a synthetic nucleoside analog of ribofuranose with activity against a wide range of viruses, especially the… Expand
National Institutes of Health

Related topics

Related topics

3 relations

Broader (1)

Ribavirin
Taribavirin Hydrochlorideanalogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2010
Review
2010
Ribavirin monitoring in chronic hepatitis C therapy: anaemia versus efficacy.
The standard treatment of HCV infection with pegylated interferon-alpha2a or -alpha2b and ribavirin is effective in <50% of HCV… Expand
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Review
2008
Review
2008
Current and future antiviral therapy of severe seasonal and avian influenza
Abstract The currently circulating H3N2 and H1N1 subtypes of influenza A virus cause a transient, febrile upper respiratory… Expand
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Review
2007
Review
2007
The kidney transplant recipient with hepatitis C infection: pre- and posttransplantation treatment.
Liver disease secondary to chronic hepatitis C virus (HCV) infection is an important cause of morbidity and mortality in dialysis… Expand
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Highly Cited
2007
Highly Cited
2007
Virological response and safety outcomes in therapy-nai ve patients treated for chronic hepatitis C with taribavirin or ribavirin in combination with pegylated interferon alfa-2a: a randomized, phase…
BACKGROUND/AIMS Pegylated interferon plus ribavirin can cause dose-limiting anemia. Taribavirin, a ribavirin prodrug, has shown a… Expand
Review
2007
Review
2007
Strategies for Managing Anemia in Hepatitis C Patients Undergoing Antiviral Therapy
Anemia is a common side effect that begins soon after the initiation of peginterferon/ribavirin in the treatment of hepatitis C… Expand
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Review
2006
Review
2006
Definition and management of anemia in patients infected with hepatitis C virus
Abstract: Chronic infection with hepatitis C virus (HCV) can progress to cirrhosis, hepatocellular carcinoma, and end‐stage liver… Expand
Highly Cited
2005
Highly Cited
2005
In vitro and in vivo influenza virus-inhibitory effects of viramidine.
Viramidine, the 3-carboxamidine derivative of ribavirin, was effective against a spectrum of influenza A (H1N1, H3N2 and H5N1… Expand
Review
2004
Review
2004
Past, present, and future hepatitis C treatments.
  • G. Foster
  • Seminars in liver disease
  • 2004
    • Corpus ID: 40079519
Conventional interferon (IFN) alfa has been used for many years in the treatment of chronic hepatitis C. However, few patients… Expand
Highly Cited
2003
Highly Cited
2003
Viramidine, a Prodrug of Ribavirin, Shows Better Liver-Targeting Properties and Safety Profiles Than Ribavirin in Animals
Ribavirin, part of the current first line combination therapy for the treatment of chronic hepatitis C, may cause haemolytic… Expand
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Review
2002
Review
2002
Prospects for hepatitis C virus therapeutics: levovirin and viramidine as improved derivatives of ribavirin.
  • J. Watson
  • Current opinion in investigational drugs
  • 2002
    • Corpus ID: 28790122
Ribavirin, in combination with interferons, has proved clinically useful for the treatment of hepatitis C virus (HCV) infection… Expand
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