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ribavirin amidine

Known as: TARIBAVIRIN, 1-beta-D-ribofuranosyl-1,2,4-triazole-3-carboxamidine, viramidine 
An orally available prodrug of ribavirin, a synthetic nucleoside analog of ribofuranose with activity against a wide range of viruses, especially the… 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (1)

Ribavirin
Taribavirin Hydrochlorideanalogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Taribavirin and 5-Fluorouracil-Loaded Pegylated-Lipid Nanoparticle Synthesis, p38 Docking, and Antiproliferative Effects on MCF-7 Breast Cancer
Breast cancer is the second most common cause of mortality in women in the United States. Targeted delivery of antitumor breast… 
Highly Cited
2009
Highly Cited
2009
A phase III study of the safety and efficacy of viramidine versus ribavirin in treatment‐naïve patients with chronic hepatitis C: ViSER1 results
Pegylated interferon (peg‐IFN) and ribavirin (RBV) are effective in eradicating the hepatitis C virus in more than half of… 
Highly Cited
2007
Highly Cited
2007
Virological response and safety outcomes in therapy-nai ve patients treated for chronic hepatitis C with taribavirin or ribavirin in combination with pegylated interferon alfa-2a: a randomized, phase…
2006
2006
751 The safety and efficacy of viramidine® plus pegylated interferon alpha-2B versus ribavirin plus pegylated interferon alpha-2B in therapy-naïve patients infected with HCV: Phase 3 results
2004
2004
Dual-Action Mechanism of Viramidine Functioning as a Prodrug and as a Catabolic Inhibitor for Ribavirin
ABSTRACT An investigational nucleoside analogue drug, viramidine, has recently emerged as a potentially safer alternative to… 
2004
2004
Disposition and Metabolic Profiles of [14C]Viramidine and [14C]Ribavirin in Rat and Monkey Red Blood Cells and Liver
ABSTRACT The disposition and metabolic profiles of [14C]viramidine and [14C]ribavirin were compared in rat and monkey red blood… 
Highly Cited
2003
Highly Cited
2003
Activation and Deactivation of a Broad-Spectrum Antiviral Drug by a Single Enzyme: Adenosine Deaminase Catalyzes Two Consecutive Deamination Reactions
ABSTRACT Ribavirin is an approved broad-spectrum antiviral drug. A liver-targeting prodrug of ribavirin, viramidine, is in… 
Review
2002
Review
2002
Prospects for hepatitis C virus therapeutics: levovirin and viramidine as improved derivatives of ribavirin.
Ribavirin, in combination with interferons, has proved clinically useful for the treatment of hepatitis C virus (HCV) infection… 
1993
1993
Treatment of lethal Pichinde virus infections in weanling LVG/Lak hamsters with ribavirin, ribamidine, selenazofurin, and ampligen.
1988
1988
Effects of ribamidine, a 3-carboxamidine derivative of ribavirin, on experimentally induced Phlebovirus infections.
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