rhodesain
National Institutes of Health
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Previously, it was suggested that the natural compound curcumin is an irreversible inhibitor of rhodesain, the major lysosomal…
Recently, it was suggested that curcumin is an irreversible inhibitor of rhodesain, a cathepsin L-like cysteine protease found in…
We have been preparing new dipeptidyl inhibitors against parasitic cysteine proteases cruzain (related to Chagas disease) and…
The dipeptidyl epoxyesters 3 and 4 are potent, irreversible inhibitors of cruzain and rhodesain.