rhodesain

 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2000-2017
024620002017

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
Rhodesain, a cathepsin L-like cysteine protease of T. brucei rhodesiense, is considered a potential target for the treatment of… (More)
Is this relevant?
2013
2013
Novel rhodesain inhibitors were obtained by combining an enantiomerically pure 3-bromoisoxazoline warhead with a specific… (More)
  • figure 1
  • figure 2
  • table 1
Is this relevant?
2010
2010
Trypanosoma cruzi and Trypanosoma brucei are parasites that cause Chagas' disease and African sleeping sickness, respectively… (More)
  • figure 1
  • figure 2
  • figure 4
  • figure 3
  • table 1
Is this relevant?
2010
2010
BACKGROUND Trypanosoma brucei is the etiological agent of Human African Trypanosomiasis, an endemic parasitic disease of sub… (More)
  • table 1
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
2008
2008
Human African trypanosomiasis (HAT) is caused by the protozoan parasite Trypanosoma brucei. The cysteine proteases of T. brucei… (More)
Is this relevant?
2007
2007
The dipeptidyl epoxyesters 3 and 4 are potent, irreversible inhibitors of cruzain and rhodesain. 
Is this relevant?
2005
2005
Herein we report the synthesis and evaluation of a series of thiosemicarbazones as potential inhibitors of cysteine proteases… (More)
Is this relevant?
2004
2004
Identification and analysis of Clan CA (papain) cysteine proteases in primitive protozoa and metazoa have suggested that this… (More)
Is this relevant?
2003
2003
While commercial isatins were practically inactive against the target proteases, thiosemicarbazone derivatives were found to be… (More)
Is this relevant?
2001
2001
Cysteine protease activity of African trypanosome parasites is a target for new chemotherapy using synthetic protease inhibitors… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?