retroviral vector

Known as: retroviral vectors 
Any one of the recombinant retroviruses (RNA viruses) designed for gene transfer applications to deliver genetic material of interest into cells… (More)
National Institutes of Health

Papers overview

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Highly Cited
2004
Highly Cited
2004
Attempts to generate reliable and versatile vectors for gene therapy and biomedical research that express multiple genes have met… (More)
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Highly Cited
2001
Highly Cited
2001
The Cre-lox system is often used to manipulate sequences in mammalian genomes. We have observed that continuous expression of the… (More)
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Highly Cited
1999
Highly Cited
1999
The expression of genes delivered by retroviral vectors is often inefficient, a potential obstacle for their widespread use in… (More)
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Highly Cited
1996
Highly Cited
1996
We describe the construction and characterization of retroviral vectors and packaging plasmids that produce helper-free… (More)
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Highly Cited
1995
Highly Cited
1995
We have constructed a series of MLV-based retroviral vectors and packaging components expressed from the CMV promoter and carried… (More)
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Highly Cited
1993
Highly Cited
1993
The restricted host-cell range and low titer of retroviral vectors limit their use for stable gene transfer in eukaryotic cells… (More)
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Highly Cited
1990
Highly Cited
1990
We report the development of an advanced system for transfer and expression of exogenous genes in mammalian cells based on… (More)
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Highly Cited
1990
Highly Cited
1990
Retroviral vectors constructed to contain the herpes simplex virus thymidine kinase (HSV-TK) gene were used for transduction of… (More)
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Highly Cited
1989
Highly Cited
1989
We describe a set of murine retrovirus-based vectors that include unique cloning sites for insertion of cDNAs such that the cDNA… (More)
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Highly Cited
1987
Highly Cited
1987
We have previously described several helper independent vector constructions (S. Hughes and E. Kosik, Virology 136:89-99, 1984; J… (More)
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