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retosiban

Known as: (3R,6R)-6-((2S)-Butan-2-yl)-3-(2,3-dihydro-1H-inden-2-yl)-1-((1R)-1-(2-methyl- 1,3-oxazol-4-yl)-2-(morpholin-4-yl)-2-oxoethyl)piperazine-2,5-dione 
 
National Institutes of Health

Papers overview

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2020
2020
CONTEXT Novel small molecule inhibitors of the oxytocin receptor (OTR) may have distinct pharmacology and mode of action when… Expand
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2018
2018
Abstract Context Stretch of the myometrium promotes its contractility and is believed to contribute to the control of parturition… Expand
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2018
2018
Myocardial infarction (MI) initiates an increase in cardiac sympathetic nerve activity (SNA) that facilitates potentially fatal… Expand
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2017
2017
Aims The aims of the present study were to investigate the maternal, fetal and neonatal safety and tolerability, pharmacodynamics… Expand
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2015
2015
AIM The aim was to investigate the efficacy and safety of intravenous retosiban in women with spontaneous preterm labour… Expand
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2015
2015
Multiple pregnancy is a major cause of spontaneous preterm birth, which is related to uterine overdistention. The objective of… Expand
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2015
2015
PURPOSE Retosiban is a small molecule oxytocin receptor antagonist that is under evaluation in clinical studies for treatment of… Expand
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2012
2012
A truly 4-component reaction! In analogy to a galaxy consisting of millions of stars a multicomponent reaction scaffold can… Expand
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2011
2011
A short, efficient and highly stereoselective synthesis has been developed for a series of 6‐indanyl‐3‐alkyl‐7‐aryl/heterocyclic… Expand
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