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retinol dehydrogenase activity

Known as: MDR, retinol:NAD+ oxidoreductase activity 
Catalysis of the reaction: retinol + NAD+ = retinal + NADH + H+. [EC:1.1.1.105]
National Institutes of Health

Papers overview

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2015
2015
Neuroleptic drugs as potential adjuvants in the treatment of MDR-TB: Minimal inhibitory concentrations (MICs) of different phenothiazines againstM. tuberculosis
Introduction: Due to an increase in resistant TB, alternative drugs that are not currently listed in the WHO guidelines on MDR TB… 
2010
2010
Reversal of multidrug resistance in murine lymphoma cells by amphiphilic dihydropyridine antioxidant derivative.
BACKGROUND Multidrug resistance, the principal mechanism by which cancer cells develop resistance to chemotherapy drugs, is a… 
2009
2009
Evaluation of (64)Cu(DO3A-xy-TPEP) as a potential PET radiotracer for monitoring tumor multidrug resistance.
In this study, we evaluated the potential of (64)Cu(DO3A-xy-TPEP) (DO3A-xy-TPEP = (2-(diphenylphosphoryl)ethyl)diphenyl(4-((4,7… 
2006
2006
99mTc-Sestamibi, A Sensitive Probe for In Vivo Imaging of P-Glycoprotein Inhibition by Modulators and mdr1 Antisense Oligodeoxynucleotides
Purpose We tested the suitability of 99mTc-sestamibi to image the inhibition of P-glycoprotein (Pgp)-mediated multidrug… 
2004
2004
Reversal of the human and murine multidrug-resistance phenotype with megestrol acetate
MA is an orally active PG derivative with an excellent safety profile that is used primarily for the treatment of carcinomas of… 
2001
2001
Structure-activity relationships and optimisation of the selective MDR modulator 2-(3,4-dimethoxyphenyl)-5-(9-fluorenylamino)-2-(methylethyl) pentanenitrile and its N-methyl derivative.
2001
2001
[Investigation on the relationship between MDR and expression of N-glycosphingolipids in vincristine resistant KBv200 cell line].
OBJECTIVE To study the relationship between MDR and expression of N-glycosphingolipids (H-GSLs) in tumor cells. METHODS… 
2000
2000
Analysis of rat cytosolic 9-cis-retinol dehydrogenase activity and enzymatic characterization of rat ADHII.
1994
1994
Correlation between the short-term measurements of drug accumulation in living cells and the long-term growth inhibition.
1994
1994
Cell-type- and developmental-stage-specific metabolism and storage of retinoids by embryonic chick retinal cells in culture.
Biological functions of retinoids in the vertebrate retina include the role of 11-cis retinaldehyde as visual pigment chromophore… 
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