FAQ

response to ionizing radiation

Known as: response to ionising radiation, response to ionizing radiation stimulus 
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1979-2017
02419792017

Papers overview

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Highly Cited
2012
Highly Cited
2012
SUMO-targeted ubiquitin E3 ligase RNF4 is required for the response of human cells to DNA damage.
Here we demonstrate that RNF4, a highly conserved small ubiquitin-like modifier (SUMO)-targeted ubiquitin E3 ligase, plays a… (More)
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2011
2011
AMPK regulates metabolism and survival in response to ionizing radiation.
BACKGROUND AND PURPOSE AMPK is a metabolic sensor and an upstream inhibitor of mTOR activity. AMPK is phosphorylated by ionizing… (More)
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2008
2008
UPLC-ESI-TOFMS-based metabolomics and gene expression dynamics inspector self-organizing metabolomic maps as tools for understanding the cellular response to ionizing radiation.
Global transcriptomic and proteomic profiling platforms have yielded important insights into the complex response to ionizing… (More)
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Highly Cited
2007
Highly Cited
2007
Human USP3 Is a Chromatin Modifier Required for S Phase Progression and Genome Stability
Protein ubiquitination is critical for numerous cellular functions, including DNA damage response pathways. Histones are the most… (More)
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2005
2005
Identification of novel p53 target genes in ionizing radiation response.
The tumor suppressor p53 plays an essential role in cellular adaptation to stress. In response to ionizing radiation, p53… (More)
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Highly Cited
2004
Highly Cited
2004
Analysis of Deinococcus radiodurans's transcriptional response to ionizing radiation and desiccation reveals novel proteins that contribute to extreme radioresistance.
During the first hour after a sublethal dose of ionizing radiation, 72 genes were upregulated threefold or higher in D… (More)
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2002
2002
Thioredoxin reductase regulates AP-1 activity as well as thioredoxin nuclear localization via active cysteines in response to ionizing radiation
A recently identified class of signaling factors uses critical cysteine motif(s) that act as redox-sensitive ‘sulfhydryl switches… (More)
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Highly Cited
2002
Highly Cited
2002
Autophosphorylation of the DNA-dependent protein kinase catalytic subunit is required for rejoining of DNA double-strand breaks.
Nonhomologous end-joining (NHEJ) is the predominant pathway that repairs DNA double-strand breaks (DSBs) in mammalian cells. The… (More)
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Highly Cited
2000
Highly Cited
2000
A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage
BACKGROUND The response of eukaryotic cells to double-strand breaks in genomic DNA includes the sequestration of many factors… (More)
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1999
1999
Different induction of adaptive response to ionizing radiation in normal and neoplastic cells
Since the beneficial effects of low-dose radiation (0.01 Gy) are usually observed in normal cells, we investigated whether the… (More)
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