replication fork arrest

Known as: negative regulation of DNA replication at replication fork barrier, replication fork blocking, replication fork stalling 
Any process that stops, prevents, or reduces the frequency, rate or extent of DNA replication by impeding the progress of the DNA replication fork… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1988-2017
0102019882017

Papers overview

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Highly Cited
2011
Highly Cited
2011
G-quadruplex (G4) DNA structures are extremely stable four-stranded secondary structures held together by noncanonical G-G base… (More)
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Highly Cited
2010
Highly Cited
2010
The initiation of eukaryotic DNA replication is regulated by three protein kinase classes: cyclin-dependent kinases (CDK), Dbf4… (More)
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2010
2010
H2AX phosphorylation at serine 139 (gammaH2AX) is a sensitive indicator of both DNA damage and DNA replication stress. Here we… (More)
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Highly Cited
2008
Highly Cited
2008
Werner syndrome is an autosomal recessive genetic instability and cancer predisposition syndrome with features of premature aging… (More)
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2007
2007
In bacteria, several salvage responses to DNA replication arrest culminate in reassembly of the replisome on inactivated forks to… (More)
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Highly Cited
2006
Highly Cited
2006
The phosphatidyl inositol 3-kinase-like kinases (PIKKs), ataxia-telangiectasia mutated (ATM) and ATM- and Rad3-related (ATR… (More)
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Highly Cited
2005
Highly Cited
2005
Genomic rearrangements linked to aberrant recombination are associated with cancer and human genetic diseases. Such recombination… (More)
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Highly Cited
2005
Highly Cited
2005
Damaged DNA, if not repaired before replication, can lead to replication fork stalling and genomic instability; however, cells… (More)
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Highly Cited
2004
Highly Cited
2004
Replication forks are arrested at specific sequences to facilitate a variety of DNA transactions. Forks also stall at sites of… (More)
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Highly Cited
1998
Highly Cited
1998
Replication arrest leads to the occurrence of DNA double-stranded breaks (DSB). We studied the mechanism of DSB formation by… (More)
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