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raf Kinases

Known as: Proteins raf, Proto-Oncogene, Proto-Oncogene Proteins raf, raf Proto-Oncogene Proteins 
A family of closely-related serine-threonine kinases that were originally identified as the cellular homologs of the retrovirus-derived V-RAF KINASES… Expand
National Institutes of Health

Papers overview

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2015
2015
Mutations in the BRAF oncogene have been identified as a tumor-initiating genetic event in mainly melanoma, thyroid and colon… Expand
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Highly Cited
2011
Highly Cited
2011
(V600E)B-RAF kinase is the most frequent onco-genic protein kinase mutation in melanoma and is a promising target to treat… Expand
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Highly Cited
2009
Highly Cited
2009
Activating B-Raf mutations that deregulate the MAPK pathway commonly occur in cancer. Whether additional proteins modulate the… Expand
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Review
2007
Review
2007
Regulation of mitochondrial apoptosis by Bcl-2 family of proteinsTo maintain the homeostasis in tissues and organs, and to… Expand
2004
2004
The deviation of the concentrations of radon decay products from equilibrium permits an estimation of the life of aerosols in the… Expand
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Review
2004
Review
2004
Bcl-2 family members are central to the control of cell survival. Work of the last years has established that the function of… Expand
Review
2002
Review
2002
Raf comprises a family of three kinases, A-Raf, B-Raf and Raf-1, which are best known as key regulators of the MEK-MAPK/ERK… Expand
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Review
1999
Review
1999
The family of Raf-protein kinases consisting of A-Raf, B-Raf, and c-Raf-1 is involved in cellular processes which regulate… Expand
1996
1996
Abstract.We have used immunocytochemistry to examine the distribution of raf protein kinases in sensory neurons of the adult rat… Expand
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