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raf Kinases
Known as:
Proteins raf, Proto-Oncogene
, Proto-Oncogene Proteins raf
, raf Proto-Oncogene Proteins
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A family of closely-related serine-threonine kinases that were originally identified as the cellular homologs of the retrovirus-derived V-RAF KINASES…
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National Institutes of Health
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Related topics
Related topics
8 relations
In Blood
Process of secretion
antagonists & inhibitors
aspects of radiation effects
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Narrower (1)
mil-raf Protein Kinases
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Die Uni-Akten der RAF-Terroristen, Gespräch mit Alexander Gallus und Reinhard Zimmermann
R. Zimmermann
2016
Corpus ID: 185729796
2015
2015
Expression of tumor-related Rac1b antagonizes B-Raf-induced senescence in colorectal cells.
A. Henriques
,
Patrícia Barros
,
M. Moyer
,
P. Matos
,
P. Jordan
Cancer letters
2015
Corpus ID: 10569834
Mutations in the BRAF oncogene have been identified as a tumor-initiating genetic event in mainly melanoma, thyroid and colon…
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Highly Cited
2011
Highly Cited
2011
Molecular Dynamics Simulation, Free Energy Calculation and Structure-Based 3D-QSAR Studies of B-RAF Kinase Inhibitors
Y. Yang
,
Jin Qin
,
Huanxiang Liu
,
X. Yao
J. Chem. Inf. Model.
2011
Corpus ID: 7041165
(V600E)B-RAF kinase is the most frequent onco-genic protein kinase mutation in melanoma and is a promising target to treat…
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Highly Cited
2009
Highly Cited
2009
C-Raf inhibits MAPK activation and transformation by B-Raf(V600E).
F. Karreth
,
G. DeNicola
,
Stephen P. Winter
,
D. Tuveson
Molecular cell
2009
Corpus ID: 34569569
Activating B-Raf mutations that deregulate the MAPK pathway commonly occur in cancer. Whether additional proteins modulate the…
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Review
2007
Review
2007
BAD association with membranes is regulated by Raf kinases and association with 14-3-3 proteins.
U. Rapp
,
A. Fischer
,
Ulrike E E Rennefahrt
,
M. Hekman
,
Š. Albert
Advances in enzyme regulation
2007
Corpus ID: 26471077
Regulation of mitochondrial apoptosis by Bcl-2 family of proteinsTo maintain the homeostasis in tissues and organs, and to…
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2004
2004
Bestimmung von Aerosolverweilzeiten aus dem RaD- und RaF-Gehalt der atmosphärischen Luft und des Niederschlags
L. Lehmann
,
A. Sittkus
Naturwissenschaften
2004
Corpus ID: 30383503
The deviation of the concentrations of radon decay products from equilibrium permits an estimation of the life of aerosols in the…
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Review
2004
Review
2004
Bcl-2 proteins: master switches at the intersection of death signaling and the survival control by Raf kinases.
U. Rapp
,
Ulrike E E Rennefahrt
,
J. Troppmair
Biochimica et biophysica acta
2004
Corpus ID: 26795060
Bcl-2 family members are central to the control of cell survival. Work of the last years has established that the function of…
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Review
2002
Review
2002
Extracellular signal regulated kinase (ERK)/mitogen activated protein kinase (MAPK)-independent functions of Raf kinases.
A. Hindley
,
W. Kolch
Journal of cell science
2002
Corpus ID: 11638988
Raf comprises a family of three kinases, A-Raf, B-Raf and Raf-1, which are best known as key regulators of the MEK-MAPK/ERK…
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Review
1999
Review
1999
Isotype-specific functions of Raf kinases.
C. Hagemann
,
U. Rapp
Experimental cell research
1999
Corpus ID: 28343025
The family of Raf-protein kinases consisting of A-Raf, B-Raf, and c-Raf-1 is involved in cellular processes which regulate…
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1996
1996
Expression of raf serine/threonine protein kinases in the cell bodies of primary sensory neurons of the adult rat
A. Mihály
,
J. Priestley
,
E. Molnár
Cell and Tissue Research
1996
Corpus ID: 12764868
Abstract.We have used immunocytochemistry to examine the distribution of raf protein kinases in sensory neurons of the adult rat…
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