FAQ

raf Kinases

Known as: Proteins raf, Proto-Oncogene, Proto-Oncogene Proteins raf, raf Proto-Oncogene Proteins 
A family of closely-related serine-threonine kinases that were originally identified as the cellular homologs of the retrovirus-derived V-RAF KINASES… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1993-2016
01219932016

Related topics

Related topics

8 relations
In BloodProcess of secretionantagonists & inhibitorschemical synthesis
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Narrower (1)

mil-raf Protein Kinases

Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
raf Kinases
physiological aspects
In Blood
chemical synthesis
standards characteristics
Process of secretion

Papers overview

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2016
2016
Design, synthesis, and in vitro antiproliferative and kinase inhibitory effects of pyrimidinylpyrazole derivatives terminating with arylsulfonamido or cyclic sulfamide substituents.
A novel series of substituted pyrimidine compounds bearing N-phenylpyrazole and terminating with aryl and cyclic sulfonamido… (More)
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Review
2015
Review
2015
A-Raf: A new star of the family of raf kinases.
The Ras-Raf-MEK-MAPK (mitogen-activated protein kinase)-signaling pathway plays a key role in the regulation of many cellular… (More)
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2014
2014
Nitrogen deposition alters plant-fungal relationships: linking belowground dynamics to aboveground vegetation change.
Nitrogen (N) deposition rates are increasing globally due to anthropogenic activities. Plant community responses to N are often… (More)
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Review
2014
Review
2014
Systemische Therapie des fernmetastasierten malignen Melanoms
Die systemische Therapie des fernmetastasierten bzw. nicht operablen malignen Melanoms hat sich in den letzten Jahren durch die… (More)
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2009
2009
C-Raf inhibits MAPK activation and transformation by B-Raf(V600E).
Activating B-Raf mutations that deregulate the MAPK pathway commonly occur in cancer. Whether additional proteins modulate the… (More)
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Review
1999
Review
1999
Isotype-specific functions of Raf kinases.
The family of Raf-protein kinases consisting of A-Raf, B-Raf, and c-Raf-1 is involved in cellular processes which regulate… (More)
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1996
1996
Expression of raf serine/threonine protein kinases in the cell bodies of primary sensory neurons of the adult rat
We have used immunocytochemistry to examine the distribution of raf protein kinases in sensory neurons of the adult rat. In… (More)
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Highly Cited
1996
Highly Cited
1996
Antitumor activity of a phosphorothioate antisense oligodeoxynucleotide targeted against C-raf kinase
Substantial evidence exists supporting a direct role for raf kinases in the development and maintenance of certain human… (More)
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1994
1994
Identification of 2 serine residues of MEK-1 that are differentially phosphorylated during activation by raf and MEK kinase.
The signal transduction kinase MEK (mitogen-activated protein (MAP) or extracellular signal-regulated (Erk) kinase)-1 is… (More)
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1993
1993
The cytoplasmic raf oncogene induces a neuronal phenotype in PC12 cells: a potential role for cellular raf kinases in neuronal growth factor signal transduction.
The neuron-like differentiation of PC12 cells is induced by nerve growth factor (NGF) through stimulation of a membrane-bound… (More)
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