rab5A GTP-Binding Protein

Known as: rab5 GTP Binding Protein, GTP-Binding Protein, rab5A, rab5 GTP-Binding Protein 
 
National Institutes of Health

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rab5 GTP-Binding Proteins

Papers overview

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2011
2011
Influence of RNA Interference Targeting Rab5a on Proliferation and Invasion of Breast Cancer Cell Line MCF-7
Objective: To explore the influence of RNA interference targeting Rab5a on proliferation and invasion of breast cancer cells, MCF… (More)
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2010
2010
Rab5a overexpression promoting ovarian cancer cell proliferation may be associated with APPL1-related epidermal growth factor signaling pathway.
Rab5a is a regulatory guanosine triphosphatase that is associated with the transport and fusion of endocytic vesicles, and… (More)
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2007
2007
The small GTPases Rab5 and RalA regulate intracellular traffic of P-glycoprotein.
P-glycoprotein (P-gp) is a plasma membrane glycoprotein that can cause multidrug resistance (MDR) of cancer cells by acting as an… (More)
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2003
2003
Agonist-induced endocytosis of lysophosphatidic acid-coupled LPA1/EDG-2 receptors via a dynamin2- and Rab5-dependent pathway.
Lysophosphatidic acid (LPA) is a serum-borne phospholipid that exerts a pleiotropic range of effects on cells through activation… (More)
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2001
2001
Regulation of epidermal growth factor receptor endocytosis by wortmannin through activation of Rab5 rather than inhibition of phosphatidylinositol 3-kinase.
The involvement of phosphatidylinositol 3-kinase (PI3K) in membrane trafficking in mammalian cells has largely come from… (More)
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2000
2000
Dynamics of rab5 activation in endocytosis and phagocytosis.
Fluid-phase endocytosis is stimulated by H-ras-linked growth factor receptors and this stimulation requires activation of rab5… (More)
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1999
1999
Dynamin and rab5 regulate GRK2-dependent internalization of dopamine D2 receptors.
Dopamine D2 receptors (D2Rs; short form, which is one of the alternative splicing variants) expressed in COS-7 cells are… (More)
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1999
1999
The small GTPases Rab5a, Rab5b and Rab5c are differentially phosphorylated in vitro.
Rab GTPases play a fundamental role in the regulation of membrane traffic. Three different Rab5 isoforms have been reported but… (More)
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1995
1995
Effect of guanine nucleotide binding on the intrinsic tryptophan fluorescence properties of Rab5.
To gain further insight into structural elements involved in Rab5 function, differences in the intrinsic tryptophan fluorescence… (More)
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Highly Cited
1994
Highly Cited
1994
Inhibition of rab5 GTPase activity stimulates membrane fusion in endocytosis.
Small GTPases of the rab family control distinct steps of intracellular transport. The function of their GTPase activity is not… (More)
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