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queuine tRNA-ribosyltransferase

Known as: queuine insertase, guanine insertion enzyme, guanine-tRNA transglycosylase 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1990-2018
01219902018

Related topics

Related topics

2 relations
QTRT1 gene

Broader (1)

pentosyltransferase

Related mentions per year

Related mentions per year

1974-2018
197019801990200020102020
queuine tRNA-ribosyltransferase
QTRT1 gene
pentosyltransferase

Papers overview

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2018
2018
Light-Activated Control of Translation by Enzymatic Covalent mRNA Labeling.
Activation of cellular protein expression upon visible-light photocleavage of small-molecule caging groups covalently attached to… (More)
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2016
2016
In vivo modification of tRNA with an artificial nucleobase leads to full disease remission in an animal model of multiple sclerosis
Queuine is a modified pyrrolopyrimidine nucleobase derived exclusively from bacteria. It post-transcriptionally replaces guanine… (More)
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2015
2015
Site-Specific Covalent Labeling of RNA by Enzymatic Transglycosylation.
We demonstrate the site-specific incorporation of nucleobase derivatives bearing fluorophores or affinity labels into a short RNA… (More)
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2009
2009
Queuosine formation in eukaryotic tRNA occurs via a mitochondria-localized heteromeric transglycosylase.
tRNA guanine transglycosylase (TGT) enzymes are responsible for the formation of queuosine in the anticodon loop (position 34) of… (More)
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2008
2008
Crystal structure of QueC from Bacillus subtilis: an enzyme involved in preQ1 biosynthesis.
To date, 107 modified nucleotides have been identified in various RNA molecules.1 These modified nucleotides, most of which occur… (More)
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2005
2005
The role of aspartic acid 143 in E. coli tRNA-guanine transglycosylase: insights from mutagenesis studies and computational modeling.
tRNA guanine transglycosylase (TGT) is a tRNA-modifying enzyme which catalyzes the posttranscriptional exchange of guanine in… (More)
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2003
2003
Chemical trapping and crystal structure of a catalytic tRNA guanine transglycosylase covalent intermediate
Prokaryotic tRNA guanine transglycosylase (TGT) catalyzes replacement of guanine (G) by 7-aminomethyl-7-deazaguanine (PreQ1) at… (More)
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2003
2003
Oscillating formation of 8-oxoguanine during DNA oxidation.
Oxidation of free guanine and guanine in salmon testes ds-DNA by hydroxyl radicals generated with Fenton reagent resulted in… (More)
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1991
1991
Structure and organization of Escherichia coli genes involved in biosynthesis of the deazaguanine derivative queuine, a nutrient factor for eukaryotes.
The plasmid pPR20 contains the gene tgt, which encodes tRNA guanine transglycosylase (Tgt), on a 33-kbp DNA insert from a region… (More)
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1990
1990
(+-)-(1 alpha,2 beta,3 alpha)-9-[2,3-bis(hydroxymethyl)-cyclobutyl] guanine [(+-)-BHCG or SQ 33,054]: a potent and selective inhibitor of herpesviruses.
(+-)-(1 alpha,2 beta,3 alpha)-9-[2,3-bis(hydroxymethyl)cyclobutyl] guanine [(+-)-BHCG or SQ 33,054] is a newly synthesized… (More)
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