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pyrrolotriazine-4-one
National Institutes of Health
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Related topics
Related topics
2 relations
Broader (2)
Pyrroles
Triazines
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
Assessing compound binding to the Eg5 motor domain using a thermal shift assay.
P. McDonnell
,
Joseph Yanchunas
,
+20 authors
D. Roussell
Analytical biochemistry
2009
Corpus ID: 24176009
Eg5 is a kinesin whose inhibition leads to cycle arrest during mitosis, making it a potential therapeutic target in cancers…
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2006
2006
Synthesis and SAR of pyrrolotriazine-4-one based Eg5 inhibitors.
K. Kim
,
Songfeng Lu
,
+24 authors
D. Roussell
Bioorganic & medicinal chemistry letters
2006
Corpus ID: 36778806
Synthesis and SAR of substituted pyrrolotriazine-4-one analogues as Eg5 inhibitors are described. Many of these analogues…
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