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pyrimidine phosphoribosyltransferase

National Institutes of Health

Papers overview

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2000
2000
Purpose: An important cytotoxic effect of 5-fluorouracil (5-FU) is the inactivation of thymidylate synthase (TS) (EC 2.1.1.45… 
1993
1993
3-Cyano-2,6-dihydroxypyridine (CNDP) was identified as a potent inhibitor (IC50 value, 4.4 nM) of dihydrouracil dehydrogenase… 
Highly Cited
1985
1972
1972
A pyrimidine phosphoribosyltransferase (approximate mol wt 100,000) with a sharply defined specificity was partially purified…