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pyrimidine phosphoribosyltransferase
Papers overview
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2000
2000
Purpose: An important cytotoxic effect of 5-fluorouracil (5-FU) is the inactivation of thymidylate synthase (TS) (EC 2.1.1.45… Expand
1993
1993
3-Cyano-2,6-dihydroxypyridine (CNDP) was identified as a potent inhibitor (IC50 value, 4.4 nM) of dihydrouracil dehydrogenase… Expand
Highly Cited
1985
Highly Cited
1985
The activities of enzymes responsible for activating 5-fluorouracil (FUra) to 5-fluorouridine-5'-monophosphate (FUMP) were… Expand
1981
1981
Rapid (6 min washing step) and reliable methods for determining uridine kinase and pyrimidine phosphoribosyltransferase… Expand
Highly Cited
1975
Highly Cited
1975
A pyrimidine phosphoribosyltransferase, previously shown to utilize 5-fluorouracil and possibly also uracil and orotate (Reyes, P… Expand
1972
1972
A pyrimidine phosphoribosyltransferase (approximate mol wt 100,000) with a sharply defined specificity was partially purified… Expand