FAQ

putrescine binding

Interacting selectively and non-covalently with putrescine, 1,4-diaminobutane, the polyamine formed by decarboxylation of ornithine and the metabolic… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1984-2018
01219842018

Papers overview

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2015
2015
A novel inhibitor of Plasmodium falciparum spermidine synthase: a twist in the tail
Plasmodium falciparum is the most pathogenic of the human malaria parasite species and a major cause of death in Africa. It’s… (More)
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2012
2012
Immunoproteomic analyses of outer membrane antigens of Actinobacillus pleuropneumoniae grown under iron-restricted conditions.
Actinobacillus pleuropneumoniae, a bacterial pathogen of swine and agent of porcine pneumonia, causes a highly infectious disease… (More)
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2009
2009
Evolution of putrescine N-methyltransferase from spermidine synthase demanded alterations in substrate binding.
Putrescine N-methyltransferase (PMT) catalyses S-adenosylmethionine (SAM)-dependent methylation of putrescine in tropane alkaloid… (More)
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2008
2008
Structural Basis for Putrescine Activation of Human S-Adenosylmethionine Decarboxylase†‡
Putrescine (1,4-diaminobutane) activates the autoprocessing and decarboxylation reactions of human S-adenosylmethionine… (More)
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2004
2004
Mammalian spermidine synthase--identification of cysteine residues and investigation of the putrescine binding site--.
Homology modeling and inhibitory studies using substrate analogs were undertaken to construct a possible three-dimensional… (More)
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2004
2004
Endogenous protein-bound polyamines: correlation with regions of cell division in tobacco leaves, internodes and ovaries
We have previously reported the binding of exogenous labeled spermidine to a developmentally regulated 18 kD protein in thin… (More)
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2002
2002
Monomeric S-adenosylmethionine decarboxylase from plants provides an alternative to putrescine stimulation.
S-Adenosylmethionine decarboxylase has been implicated in cell growth and differentiation and is synthesized as a proenzyme… (More)
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2002
2002
Putrescine activation of Trypanosoma cruzi S-adenosylmethionine decarboxylase.
S-Adenosylmethionine decarboxylase (AdoMetDC) is a pyruvoyl-dependent enzyme that is processed from a single polypeptide into two… (More)
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1999
1999
Cloning and kinetic characterization of the Trypanosoma cruzi S-adenosylmethionine decarboxylase.
The gene for S-adenosylmethionine decarboxylase (AdoMetDC), a rate-limiting enzyme in the biosynthesis of polyamines, has been… (More)
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1990
1990
Effects of a series of homologous alpha,omega-dimethylaminoalkanes on cell proliferation: binding and uptake of putrescine by a human glioblastoma cell line (U251) in culture.
The first step of polyamine uptake is the binding of polyamines to the cell membrane. In order to characterize the specificity of… (More)
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