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purine imidazole-ring cyclase activity

Known as: DNA-4,6-diamino-5-formamidopyrimidine 8-C,9-N-lyase (cyclizing), DNA-4,6-diamino-5-formamidopyrimidine 8-C,9-N-lyase (cyclizing; DNA-adenine-forming), DNA-4,6-diamino-5-formamidopyrimidine C8-N9-lyase (cyclizing; DNA-adenine-forming) 
Catalysis of the reaction: DNA 4,6-diamino-5-formamidopyrimidine = DNA adenine + H2O. [EC:4.3.2.4, MetaCyc:PURINE-IMIDAZOLE-RING-CYCLASE-RXN]
National Institutes of Health

Papers overview

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2018
2018
Synthesis of eunicellane-type bicycles embedding a 1,3-cyclohexadiene moiety
The first synthesis of diterpenoid eunicellane skeletons incorporating a 1,3-cyclohexadiene moiety is presented. Key step is a… 
2016
2016
3-Alkylperoxy-3-cyano-oxindoles from 2-Cyano-2-diazo-N-phenyl-acetamides via Cyclizing Carbene Insertion and Subsequent Radical Oxidation.
A transition-metal-free one-pot sequence for the synthesis of 3-peroxy-substituted oxindoles from readily prepared 2-cyano-2… 
2016
2016
The stereodivergent formation of 2,6-cis and 2,6-trans-tetrahydropyrans: experimental and computational investigation of the mechanism of a thioester oxy-Michael cyclization
Computational and synthetic studies have elucidated the origins of stereodivergence in an oxy-Michael synthesis of 2,6… 
2015
2015
Moonlighting Metals: Insights into Regulation of Cyclization Pathways in Fungal Δ6‐Protoilludene Sesquiterpene Synthases
Fungal 1,11 cyclizing sesquiterpene synthases are product specific under typical reaction conditions. However, in vivo expression… 
2013
2013
New approaches to functionalizing metal-coordinated N2.
Catalytic conversion of N2 into value-added products is the challenge of attack on a refractory molecule. We develop herein ideas… 
Highly Cited
2002
Highly Cited
2002
Synthesis, cytotoxicity, and antiplasmodial and antitrypanosomal activity of new neocryptolepine derivatives.
On the basis of the original lead neocryptolepine or 5-methyl-5H-indolo[2,3-b]quinoline, an alkaloid from Cryptolepis… 
Highly Cited
2000
Highly Cited
2000
Induction of an extracellular cyclic nucleotide phosphodiesterase as an accessory ribonucleolytic activity during phosphate starvation of cultured tomato cells.
During growth under conditions of phosphate limitation, suspension-cultured cells of tomato (Lycopersicon esculentum Mill… 
1988
1988
Monoterpene biosynthesis: demonstration of a geranyl pyrophosphate:sabinene hydrate cyclase in soluble enzyme preparations from sweet marjoram (Majorana hortensis).
1986
1986
Purification, molecular and enzymic characterization of an acid RNase from the insect Ceratitis capitata.
An acid ribonuclease has been purified from the insect Ceratitis capitata. The specific activity of the purified enzyme is 580… 
1958
1958
Synthesis of 1-tertalkyl-6,7-dimethoxyisoquinolines.
A series of 1-tert-alkyl-6, 7-dimethoxy-3, 4-dihydroisoquinolines was synthesized in high yields by cyclizing N-(3, 4… 
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