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pteridine reductase 1

Known as: PTR1 pteridine reductase 
National Institutes of Health

Papers overview

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2017
2017
Flavonoids have previously been identified as antiparasitic agents and pteridine reductase 1 (PTR1) inhibitors. Herein, we focus… Expand
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2011
2011
Leishmania parasites are pteridine auxotrophs that use an NADPH-dependent pteridine reductase 1 (PTR1) and NADH-dependent… Expand
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2011
2011
Genetic studies indicate that the enzyme pteridine reductase 1 (PTR1) is essential for the survival of the protozoan parasite… Expand
2010
2010
Activity of the pterin- and folate-salvaging enzymes pteridine reductase 1 (PTR1) and dihydrofolate reductase–thymidylate… Expand
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Highly Cited
2009
Highly Cited
2009
The enzyme pteridine reductase 1 (PTR1) is a potential target for new compounds to treat human African trypanosomiasis. A virtual… Expand
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Highly Cited
2006
Highly Cited
2006
Background Recent circumstantial evidence suggests that an increasing number of Iranian patients with cutaneous leishmaniasis are… Expand
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2003
2003
Pteridine metabolism in Trypanosoma cruzi is poorly understood. The term ‘pteridine’ is used collectively for two classes of… Expand
1999
1999
The enzyme pteridine reductase (PTR1) has recently been discovered in the protozoan parasite Leishmania and validated as a target… Expand
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1998
1998
Pteridine reductase 1 (PTR1) is a novel broad spectrum enzyme of pterin and folate metabolism in the protozoan parasite… Expand
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Review
1997
Review
1997
Leishmania and other trypanosomatid protozoa require reduced pteridines (pterins and folates) for growth, suggesting that… Expand
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