prucalopride
National Institutes of Health
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Abstract Objective To formulate timely evidence-based guidelines for the management of opioid-induced bowel dysfunction. Setting…
BackgroundPrucalopride, a selective, high-affinity 5-hydroxytryptamine 4 receptor agonist, stimulates gastrointestinal and…
The 5‐HT4 receptor agonist prucalopride is a prokinetic drug which improves colonic motility. Animal data and in vitro studies…
BACKGROUND & AIMS
Prucalopride is a selective, high-affinity agonist of the 5-hydroxytryptamine (serotonin) receptor 4 that…
Background Although constipation can be a chronic and severe problem, it is largely treated empirically. Evidence for the…
INTRODUCTION Constipation is a chronic problem in many patients all over the world. In some groups of patients such as the…
Obestatin, encoded by the ghrelin gene may inhibit gastrointestinal (GI) motility. This activity was re‐investigated.
Background : Laxatives are frequently ineffective in treating constipation. An alternative therapeutic approach is to target…
BACKGROUND Prucalopride (R093877) is a selective and specific 5HT4 agonist, the first of a new chemical class of benzofurans…