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prucalopride

 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1999-2017
010203019992017

Related topics

Related topics

3 relations

Broader (1)

Benzofurans

Narrower (2)

R 093877Resolor

Related mentions per year

Related mentions per year

1960-2018
1960198020002020
prucalopride
Benzofurans
R 093877
Resolor

Papers overview

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2010
2010
A double-blind, placebo-controlled study of prucalopride in elderly patients with chronic constipation.
BACKGROUND Constipation affects up to 50% of the elderly; this study evaluates the efficacy, safety, and tolerability of the… (More)
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Highly Cited
2009
Highly Cited
2009
Prucalopride (Resolor) in the treatment of severe chronic constipation in patients dissatisfied with laxatives.
OBJECTIVE To determine the efficacy, impact on quality of life (QOL) and safety of prucalopride, a selective, high-affinity 5-HT… (More)
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Highly Cited
2009
Highly Cited
2009
Clinical trial: the efficacy, impact on quality of life, and safety and tolerability of prucalopride in severe chronic constipation--a 12-week, randomized, double-blind, placebo-controlled study.
BACKGROUND Chronic constipation may result in disabling symptoms, is often unsatisfactorily treated by laxatives and negatively… (More)
Is this relevant?
2009
2009
Safety assessment of prucalopride in elderly patients with constipation: a double-blind, placebo-controlled study.
Chronic constipation is common among nursing home residents. The aim of this study was to evaluate safety, tolerability and… (More)
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Highly Cited
2008
Highly Cited
2008
A placebo-controlled trial of prucalopride for severe chronic constipation.
BACKGROUND In this 12-week trial, we aimed to determine the efficacy of prucalopride, a selective, high-affinity 5… (More)
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2008
2008
Prucalopride and donepezil act synergistically to reverse scopolamine-induced memory deficit in C57Bl/6j mice.
It is known that 5-HT(4) receptor agonists increase sAPPalpha levels in the cortex and hippocampus of mice as well as in a model… (More)
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2002
2002
Effects of prucalopride on colonic transit, anorectal function and bowel habits in patients with chronic constipation.
BACKGROUND There is a need for better tolerated drugs to normalize bowel function in chronic constipation. Prucalopride is a… (More)
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Highly Cited
2001
Highly Cited
2001
Prucalopride accelerates gastrointestinal and colonic transit in patients with constipation without a rectal evacuation disorder.
BACKGROUND & AIMS Prucalopride (PRU) is a selective benzofuran 5-hydroxytryptamine(4)-receptor agonist with gastrointestinal and… (More)
Is this relevant?
2001
2001
Effects of the enterokinetic prucalopride (R093877) on colonic motility in fasted dogs.
The novel enterokinetic drug prucalopride was tested at various intravenous and oral doses in fasted dogs to assess: (i) the… (More)
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Highly Cited
1999
Highly Cited
1999
Selective stimulation of colonic transit by the benzofuran 5HT4 agonist, prucalopride, in healthy humans.
BACKGROUND Prucalopride (R093877) is a selective and specific 5HT4 agonist, the first of a new chemical class of benzofurans… (More)
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