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prucalopride
Â
National Institutes of Health
Topic mentions per year
Topic mentions per year
1999-2017
0
10
20
30
1999
2017
Related topics
Related topics
3 relations
Broader (1)
Benzofurans
Narrower (2)
R 093877
Resolor
Related mentions per year
Related mentions per year
1960-2018
1960
1980
2000
2020
prucalopride
Benzofurans
R 093877
Resolor
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2010
2010
A double-blind, placebo-controlled study of prucalopride in elderly patients with chronic constipation.
Stefan A. Müller-Lissner
,
An Rykx
,
Robin Kerstens
,
Lieve Vandeplassche
Neurogastroenterology and motility : the official…
2010
BACKGROUND Constipation affects up to 50% of the elderly; this study evaluates the efficacy, safety, and tolerability of the…Â
(More)
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Highly Cited
2009
Highly Cited
2009
Prucalopride (Resolor) in the treatment of severe chronic constipation in patients dissatisfied with laxatives.
Jan Tack
,
Marc J Van Outryve
,
Greet Beyens
,
Robin Kerstens
,
Lieve Vandeplassche
Gut
2009
OBJECTIVE To determine the efficacy, impact on quality of life (QOL) and safety of prucalopride, a selective, high-affinity 5-HT…Â
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Highly Cited
2009
Highly Cited
2009
Clinical trial: the efficacy, impact on quality of life, and safety and tolerability of prucalopride in severe chronic constipation--a 12-week, randomized, double-blind, placebo-controlled study.
Eamonn M. M. Quigley
,
Lieve Vandeplassche
,
Robin Kerstens
,
Jannie Ausma
Alimentary pharmacology & therapeutics
2009
BACKGROUND Chronic constipation may result in disabling symptoms, is often unsatisfactorily treated by laxatives and negatively…Â
(More)
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2009
2009
Safety assessment of prucalopride in elderly patients with constipation: a double-blind, placebo-controlled study.
Michael J. Camilleri
,
Greet Beyens
,
Robin Kerstens
,
P. Robinson
,
Lieve Vandeplassche
Neurogastroenterology and motility : the official…
2009
Chronic constipation is common among nursing home residents. The aim of this study was to evaluate safety, tolerability and…Â
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Highly Cited
2008
Highly Cited
2008
A placebo-controlled trial of prucalopride for severe chronic constipation.
Michael J. Camilleri
,
René Kerstens
,
An Rykx
,
Lieve Vandeplassche
The New England journal of medicine
2008
BACKGROUND In this 12-week trial, we aimed to determine the efficacy of prucalopride, a selective, high-affinity 5…Â
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2008
2008
Prucalopride and donepezil act synergistically to reverse scopolamine-induced memory deficit in C57Bl/6j mice.
Marthe Cachard-Chastel
,
Séverine Devers
,
+4 authors
Catherine Belzung
Behavioural brain research
2008
It is known that 5-HT(4) receptor agonists increase sAPPalpha levels in the cortex and hippocampus of mice as well as in a model…Â
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2002
2002
Effects of prucalopride on colonic transit, anorectal function and bowel habits in patients with chronic constipation.
Cornelius EJ Sloots
,
Alexander C. Poen
,
+5 authors
Richel-J Felt-Bersma
Alimentary pharmacology & therapeutics
2002
BACKGROUND There is a need for better tolerated drugs to normalize bowel function in chronic constipation. Prucalopride is a…Â
(More)
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Highly Cited
2001
Highly Cited
2001
Prucalopride accelerates gastrointestinal and colonic transit in patients with constipation without a rectal evacuation disorder.
Ernest P. Bouras
,
M Camilleri
,
Duane D. Burton
,
George M. Thomforde
,
Sanna McKinzie
,
Alan R. Zinsmeister
Gastroenterology
2001
BACKGROUND & AIMS Prucalopride (PRU) is a selective benzofuran 5-hydroxytryptamine(4)-receptor agonist with gastrointestinal and…Â
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2001
2001
Effects of the enterokinetic prucalopride (R093877) on colonic motility in fasted dogs.
Martijn Briejer
,
Nicolaas H Prins
,
J. A. J. Schuurkes
Neurogastroenterology and motility : the official…
2001
The novel enterokinetic drug prucalopride was tested at various intravenous and oral doses in fasted dogs to assess: (i) the…Â
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Highly Cited
1999
Highly Cited
1999
Selective stimulation of colonic transit by the benzofuran 5HT4 agonist, prucalopride, in healthy humans.
Ernest P. Bouras
,
M Camilleri
,
Duane D. Burton
,
Sanna McKinzie
Gut
1999
BACKGROUND Prucalopride (R093877) is a selective and specific 5HT4 agonist, the first of a new chemical class of benzofurans…Â
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