prucalopride
National Institutes of Health
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The nonselective 5‐HT4 receptor agonists, cisapride and tegaserod have been associated with cardiovascular adverse events (AEs).
Background Although constipation can be a chronic and severe problem, it is largely treated empirically. Evidence for the…
Background Constipation affects up to 50% of the elderly; this study evaluates the efficacy, safety, and tolerability of the…
BackgroundOpioid-induced constipation (OIC) has negative effects on quality of life (QOL). Prucalopride is a new, selective 5-HT4…
Background Chronic constipation may result in disabling symptoms, is often unsatisfactorily treated by laxatives and negatively…
BACKGROUND
In this 12-week trial, we aimed to determine the efficacy of prucalopride, a selective, high-affinity 5…
Objective: To determine the efficacy, impact on quality of life (QOL) and safety of prucalopride, a selective, high-affinity 5…
Obestatin, encoded by the ghrelin gene may inhibit gastrointestinal (GI) motility. This activity was re‐investigated.
BACKGROUND & AIMS
Prucalopride (PRU) is a selective benzofuran 5-hydroxytryptamine(4)-receptor agonist with gastrointestinal and…